Freqüência e atividade enzimática de Candida spp. na cavidade oral de pacientes diabéticos do serviço de endocrinologia de um hospital de Fortaleza-CE

Menezes, Everardo Albuquerque; Augusto, Kristopherson Lustosa; Freire, Caio Castro; Cunha, Francisco Afrânio; Montenegro, Renan Magalhães; Júnior, Renan Magalhães Montenegro

doi:10.1590/s1676-24442007000400004

Cited by 6 publications

(4 citation statements)

References 8 publications

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“…2009 ). A high frequency of colonisation in diabetic patients has been previously observed ( Menezes et al 2007 , Sashikumar & Kannan 2010 , Obradović et al 2011) . In addition, Colombo et al (2012) reported that diabetes mellitus is one of the most common pathological disorders predisposing adult patients to the development of different clinical forms of candidiasis.…”

Section: Discussionmentioning

confidence: 77%

Analysis of the genetic diversity of Candida isolates obtained from diabetic patients and kidney transplant recipients

Benedetti

Savi

Aluízio

et al. 2016

Mem. Inst. Oswaldo Cruz

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Yeasts of the genus Candida have high genetic variability and are the most common opportunistic pathogenic fungi in humans. In this study, we evaluated the genetic diversity among 120 isolates of Candida spp. obtained from diabetic patients, kidney transplant recipients and patients without any immune deficiencies from Paraná state, Brazil. The analysis was performed using the ITS1-5.8S-ITS2 region and a partial sequence of 28S rDNA. In the phylogenetic analysis, we observed a consistent separation of the species C. albicans, C. dubliniensis, C. glabrata, C. tropicalis, C. parapsilosis, C. metapsilosis and C. orthopsilosis, however with low intraspecific variability. In the analysis of the C. albicans species, two clades were formed. Clade A included the largest number of isolates (91.2%) and the majority of isolates from GenBank (71.4%). The phylogenetic analysis showed low intraspecific genetic diversity, and the genetic polymorphisms between C. albicans isolates were similar to genetic divergence found in other studies performed with isolates from Brazil. This low genetic diversity of isolates can be explained by the geographic proximity of the patients evaluated. It was observed that yeast colonisation was highest in renal transplant recipients and diabetic patients and that C. albicans was the species most frequently isolated.

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Section: Discussionmentioning

confidence: 77%

Analysis of the genetic diversity of Candida isolates obtained from diabetic patients and kidney transplant recipients

Benedetti

Savi

Aluízio

et al. 2016

Mem. Inst. Oswaldo Cruz

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“…In Brazil, studies found that 51.1% of analyzed C. albicans samples showed phospholipase activity (40,41). Percentages are variable in relation to activity detection, with values of 73.3, 96.6, and even 100% of samples (36,39,42).…”

Section: Discussionmentioning

confidence: 99%

Pathogenic characteristics of yeasts isolated from vaginal secretion preserved under mineral oil

Gomes¹,

Souza-Motta²,

Lima³

et al. 2011

J. Venom. Anim. Toxins incl. Trop. Dis

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Abstract:In order to evaluate the pathogenicity of yeasts isolated from vaginal secretion of pregnant and non-pregnant women -stored in mineral oil at the URM Mycology Collection, Department of Mycology, Federal University of Pernambuco -30 samples belonging to the genera Candida, Rhodotorula, Trichosporon, and Kloeckera, were studied regarding their pathogenic characteristics, ability to grow at room temperature (28°C ± 1°C), 37°C, and 42°C for 72 hours, and production of both phospholipase and proteinase. Results showed that all 30 isolates (100%) were able to grow at room temperature and 37°C, and that 17 samples (57%) were able to grow at 42°C. Evaluation of enzymatic activity showed protease activity in only two isolates (7%), namely C. maritima and C. obtusa. Phospholipase activity was detected in 20 isolates (67%) using soy lecithin as substrate at different temperatures. The characterization of yeasts isolated from vaginal secretion and determination of their enzymatic activity may contribute to understanding the epidemiology of vulvovaginitis and assist in the treatment of patients.

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“…Após o crescimento, as leveduras foram semeadas em meio cromógeno e incubadas a 35°C por 24-48 horas, com o objetivo de garantir a pureza dos isolados. Nas cepas sugestivas de C. parapsilosis, foram realizadas as técnicas manuais e convencionais de fermentação, assimilação de carboidratos e micromorfologia em ágar arroz com tween 80 (12,16,22,30) .…”

Section: Identificação Bioquímica E Micromorfologia De C Parapsilosisunclassified

“…Nos últimos anos, C. parapsilosis vem sendo isolada em diversos estudos realizados no Ceará, Nordeste do Brasil (12,15,16,30) . O objetivo do nosso estudo foi identificar e avaliar, por métodos fenotípicos e moleculares, a suscetibilidade dessa levedura aos antifúngicos anfotericina B, caspofungina, fluconazol, itraconazol e voriconazol de amostras isoladas desse estado brasileiro.…”

Section: Introductionunclassified

Identificação molecular e suscetibilidade antifúngica de Candida parapsilosis isoladas no Ceará, Brasil

Menezes¹,

Júnior²,

Cunha³

et al. 2012

J. Bras. Patol. Med. Lab.

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Freqüência e atividade enzimática de Candida spp. na cavidade oral de pacientes diabéticos do serviço de endocrinologia de um hospital de Fortaleza-CE

Cited by 6 publications

References 8 publications

Analysis of the genetic diversity of Candida isolates obtained from diabetic patients and kidney transplant recipients

Analysis of the genetic diversity of Candida isolates obtained from diabetic patients and kidney transplant recipients

Pathogenic characteristics of yeasts isolated from vaginal secretion preserved under mineral oil

Identificação molecular e suscetibilidade antifúngica de Candida parapsilosis isoladas no Ceará, Brasil

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