Leiomioma vascular bucal: relato de dois casos, revisão da literatura e estudo imuno-histoquímico

Abstract

J Bras Patol Med Lab • v. 43 • n. 3 • p. 211-217 • junho 2007 unitermos key words resumo Introdução: Os leiomiomas são neoplasias benignas do músculo liso que ocorrem mais comumente nos tratos geniturinário e gastrintestinal, entretanto são raros na cavidade bucal, na qual provavelmente a maioria desses tumores tem sua origem a partir de músculo liso vascular. Objetivos: Relatar dois casos com história clínica semelhante, confrontando seus aspectos com aqueles encontrados na literatura. Relato dos casos: Dois casos de mulheres na quinta e sexta décadas de vida apresentando nódulo submucoso em ventre lingual. Após exame microscópico que revelou numerosos vasos sangüíneos entremeados a células fusiformes, com núcleos ovalados ou alongados, e exame imuno-histoquímico com positividade para actina de músculo liso nos dois casos, o diagnóstico final foi leiomioma vascular. Conclusão: O estudo do leiomioma vascular bucal é de extrema importância devido à raridade e semelhança desse com outras lesões da cavidade bucal. A análise imuno-histoquímica é importante para o diagnóstico final do leiomioma. Leiomioma

Vascular leiomyoma in the oral cavity – Report of two cases

“…Silva et al (5) reviewed the oral VL cases published between 2011 and 2016 and found 17 cases, with gingiva as the most common involved anatomical site. Of 14,056 cases diagnosed in our Oral Pathology service, within a 57-year interval, only 5 cases (0.036%) of VL were found ( Table 1), of which two have already been published (6). The mean age of our patients was 52.6 ± 12.52 years, slightly older than other series (4,5), with a predominance of males (3:2), in agreement with the data in the literature (4,5).…”

Vascular leiomyoma affecting the lip: report of a case and an updated analysis of the 78 cases reported in the literature

“…The head and neck region lack smooth muscle; therefore the occurrence of VL in this area is extremely rare, accounting for less than 1% of all lesions (1)(2)(3)(4)(5). The most frequent locations in the oral cavity are the lips and the tongue (4)(5)(6)(7).…”

“…The color may vary from pale red to purplish, and the size rarely exceeds two centimeters (7)(8)(9)(10). Due to the clinical presentation, VLL may mimic other mesenchymal or salivary gland tumor-like lesions, as well as traumatic lesions (3)(4)(5)(6)(7).…”

“…Even with these well-defined variables, immunohistochemical analysis is necessary in some cases to define the diagnosis and conduct the treatment. Conservative surgical excision is the treatment of choice, and the prognosis is excellent (2)(3)(4)(5)(6)(7)11).…”