Effects of the Electromagnetic field, 60 Hz, 3 µT, on the hormonal and metabolic regulation of undernourished pregnant rats

Abstract

Epidemiological studies have implicated maternal protein-calorie deficiency as an important public health problem in developing countries. Over the last decades, a remarkable diffusion of electricity and an increased level of the electromagnetic field (EMF) in the environment have characterized modern societies. Therefore, researchers are concerned with the biological effects of 50-60 Hz, EMF. The aim of this paper is to show the effects of EMF of 60 Hz, 3 µT, exposure for two hours per day in the regulation of the hormonal and metabolic concentrations in pregnant rats, which were fed by Regional Basic Diet (RBD) during their pregnancy as compared with pregnant rats fed a standard diet. Pregnant rats exposed to EMF of 60 Hz, 3 µT, over the pregnancy and fed with RBD presented an increase in glucose release when compared with the Group subjected only to the RBD ration. Rats fed RBD presented a decrease in their insulin and cortisol serum levels when compared with the Group fed with casein. The T 3 and T 4 concentrations presented the greatest variation among the Groups. The relation T 4 :T 3 was much exaggerated in the Group subjected to RDB and exposed to EMF when compared to the others. In conclusion, the group subjected to the association of EMF and undernutrition suffered a decrease in its serum concentration of T 4 and T 3 when compared to the well-nourished group and the relationship T 4 :T 3 in the former group was almost eighteen-fold the later one.Keywords: casein, electromagnetic field, metabolism, hormone, regional basic diet, undernourished pregnant rats. Efeitos do campo eletromagnético, 60 Hz, 3µT, na regulação hormonal e metabólica de ratas prenhes desnutridas ResumoEstudos epidemiológicos têm mostrado que a deficiência proteico-calórica é um importante problema nos países em desenvolvimento. Durante as últimas décadas, a sociedade moderna tem sido caracterizada pelo aumento no número de equipamentos elétricos e como consequência um aumento no nível do campo eletromagnético (CEM) no ambiente. No entanto, os pesquisadores estão preocupados com os efeitos biológicos dos CEM de 50-60 Hz. O objetivo deste artigo é mostrar os efeitos do CEM de 60 Hz, 3 µT, nas concentrações hormonais e metabólicas de ratas prenhes, expostas duas horas por dia ao CEM, alimentadas pela Dieta Básica Regional (DBR) comparando com ratas submetidas às mesmas condições, mas alimentas com dieta padrão. Ratas prenhes expostas ao CEM de 60 Hz, 3 µT, durante a prenhez e alimentadas com a DBR apresentaram um aumento na liberação de glicose quando comparadas com o grupo alimentado pela DBR sem CEM. As ratas alimentadas pela DBR apresentaram uma diminuição nos níveis de insulina e cortisol quando comparadas com o grupo alimentado pela caseína. As concentrações de T 3 e T 4 apresentaram a maior variação entre os grupos. A relação T 4 :T 3 foi muito exagerada no grupo alimentado pela DBR e exposto ao CEM quando comparado com os outros. Conclusão, os animais que foram submetidos à desnutrição e ao CEM sofreram uma diminuição na ...

Evaluation of skeletal muscle regeneration in experimental model after malnutrition

“…The animals exposed to a low protein diet had a reduction in insulin secretion, probably as a consequence of deficient Ca 2+ absorption in pancreatic cells. Anselmo et al (2009) evaluated rats subjected to a multi-deficient diet during pregnancy and observed a reduction in insulin levels and cortisol compared with the control group (18% casein). After the recovery period (45 days), the MR group had similar food intake and body weight compared with the N group.…”

Thyroid Hormone Indices in Computer Workers with Emphasis on the Role of Zinc Supplementation

“…Maxwell and Volpe [ 39 ] found that, although metabolic rates and thyroid hormone levels of two zinc-deficient subjects were comparable, zinc supplementation (26.4 mg/day as zinc gluconate) increased both free and total T3 and T4 levels in one subject, and only total T3 increased in the other subject at four months, however resting metabolic rate was increased in both. On the other hand some other researchers showed increase in serum TSH, FT3 and FT4 concentrations [ 40 , 41 ]. Selmaoui et al [ 42 ] reported that there was insignificant difference in T3 and T4 between non-exposed males and men exposed to continuous and intermittent 50 Hz magnetic field of ten Tesla overnight.…”

Molecular transduction in receptor-ligand systems by planar electromagnetic fields

“…As a precondition for generating any electromagnetic field, the movement of electrical charge is required (Anselmo et al, 2008;Anselmo et al, 2009). Aromatic residues possess electrons in movement, able to instigate such a field.…”