Cancer survival among children and adolescents at a state referral hospital in southeastern Brazil

Abstract

OBJECTIVES: to analyze the patient characteristics and evaluate overall survival, survival according to demographic variables, the most common tumor groups and subgroups, the stages of disease, and risk factors after at least 5 years among children and adolescents with cancer who were admitted to a state referral hospital between 2000 and 2005. METHODS: the Kaplan-Meier method was employed to estimate survival. The survival curves were compared using the log-rank test. The Cox regression model was used to estimate the effect of independent variables. RESULTS: a total of 571 new cases were registered. The most frequent cancer groups were leukemia (34%), lymphoma (18%), and central nervous system (CNS) tumors (15%).The overall survival rate was 59%. The risk factors associated with lower survival were an age of more than 4 years or less than 1 year, the presence of CNS tumors, and non-localized disease. CONCLUSION: although this was not a populationbased study, it provides important epidemiological information about a state where population data on childhood and adolescent cancer are scarce and where hospital-based data do not exist. The survival rate found here should serve as a framework for future improvements, helping to guide policymakers focused on pediatric oncology in the state.

Association Between Oral Diseases And Sociodemographic Variables In Children And Adolescents With Cancer

“…In this study, there was a predominance of individuals aged 1-4 years, which is in agreement with the findings of a study conducted in Espírito Santo 19 and another in Salvador, Bahia 14 , but different from a study conducted in Recife (Brazil) 9 . This predominance of cases of malignant neoplasms in early age groups should be taken into account, since the younger the patient, the greater the possibility of chemotherapeutic treatment affecting the oral cavity 5,7 .…”

“…Regarding sex, a predominance of males in cancer patients was observed in this study, which is in agreement with the results of several national and international studies 1,9,10,15,16,17,18 . In an international study, the number of children and adolescents with cancer was equal for both sexes 19 .…”

Sobrevivência do câncer entre crianças e adolescentes em um serviço brasileiro de referência

“…In the Cox Regression analysis for survival of these four major groups significant differences in survival time were found in terms of diagnostic Groups adjusted for age and sex (p=0.001), similar to studies in developing countries (Gatta et al, 2014;Zouain-Figueiredo, Zandonade & Amorim, 2013).…”

Impacto físico e psicossocial na criança com câncer em tratamento: avaliando sua qualidade de vida

“…Esses resultados têm sido uma constante em diversos países do mundo, incluindo o Brasil, mesmo com características étnica, geográfica, cultural e econômica diferentes. [2][3][4][5][6][7][8][9][10][11][12][13][14][15] Evidenciou-se que as mães ainda são as principais cuidadoras em momentos em que há a presença de doença ou aumento de alguma necessidade da criança. 16 Outro resultado importante foi a média de idade do cuidador, 33,1 anos, mas com desvio padrão de 8,8, ressaltando uma realidade populacional brasileira que se mantém: mães em idades bastante precoces.…”