Anti-Helicobacter pylori activity of plant extracts traditionally used for the treatment of gastrointestinal disorders

Abstract

The antibacterial activity of plant extracts obtained from Bixa orellana L., Chamomilla recutita L., Ilex paraguariensis A. St.-Hil., Malva sylvestris L., Plantago major L. and Rheum rhaponticum L. has been evaluated against two reference strains and eleven clinical isolates of Helicobacter pylori. All the plant species chosen are used in popular Brazilian cuisine and folk medicine in the treatment of gastrointestinal disorders. Initial screening was made by the disk diffusion test and then minimum inhibitory concentration was determined by the agar dilution method. The results presented in this work demonstrated that among the plant preparations analyzed, B. orellana L., C. recutita L., I. paraguariensis A. St.-Hil. and M. sylvestris L. were capable of inhibiting the in vitro growth of H. pylori.

Lack of Association Between Helicobacter Pylori's Virulence and Increased Serum C-Reactive Protein Levels in Functional Dyspeptic Patients

“…The infusion is shared by different people using the same gourd and straw. Although it has been reported that the herb presents anti-H. pylory activity (6) , this cultural habit may provide a possible route for the bacterial transmission.…”

“…The infusion is shared by different people using the same gourd and straw. Although it has been reported that the herb presents anti-H. pylory activity (6) , this cultural habit may provide a possible route for the bacterial transmission.Considering our study procedures, we recognize that CRP is an unspecific marker of acute inflammation and that it can be related to a several diseases and conditions. Firstly described by Tillett e Francis (1930), this inflammatory protein has an important role to predict the cardiovascular risk, among other applications (31,39) .…”

“…Studies have reported that several aspects can be related to incidence and prevalence rates like socioeconomic status, years of study, institutionalization practice or social habits (8,20) . In 2010, a Brazilian study has demonstrated an anti-H. pylori activity of plant extracts, like yerba maté tea (Ilex paraguariensis), but no association between bacteria prevalence and tea consumption has been previously described (6) . Andreolla HF, Bona LR, Sander GB, Mazzoleni LE, Tavares RG, Prolla JC.…”

Malva: Food, Medicine and Chemistry

“…266 Synergism of plant powder and charcoal yielded high removal of Hg(II) from aqueous solutions 267 Antimicrobial, antibacterial, antifungal Whole plant extract (96% EtOH/Water, traditionally used to treat gastrointestinal disorders) found active against Helicobacter pylori. 268 Methanolic extract of aerial parts and three fotmulations of it were tested against several bacteria. The extract was very active gainst S. aureus.…”

Comparison of three different regimens against Helicobacter pylori as a first-line treatment: A randomized clinical trial

“…The bacterium induces chronic inflammation of the underlying mucosa and typically infects the stomach in the first few years of life. It was isolated for the first time by Marshall and Warren [1]. It survives in the acidic environment of the gastric mucosa and causes gastritis, peptic ulcers, mucosa-associated lymphoid tissue lymphoma, and gastric cancer [2].…”