HLA in Brazilian Ashkenazic Jews with chronic dermatophytosis caused by Trichophyton rubrum

Sadahiro, Aya; Moraes, José Geraldo Vinci de; Moraes, M. E.; Romero, Matilde; Gouvea, Nancy Alves de Lima; Gouvea, Celso José; Ogusku, Maurício Morishi; Campbell, Iphis; Zaitz, Clarisse

doi:10.1590/s1517-83822004000100011

Cited by 17 publications

(10 citation statements)

References 21 publications

(19 reference statements)

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“…[22] In several Indian studies, T. rubrum remain the commonest dermatophytes. [23] The predominant dermatophyte in a particular geographical area varies probably due to different geographical condition, environmental temperature, rainfall and humidity. T. rubrum is generally linked to chronic dermatophytosis.…”

Section: Discussionmentioning

confidence: 99%

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Clinico-Mycological Profile of Onychomycosis in a Tertiary Care Centre of Tripura

Debbarma¹,

Barman²,

Majumdar³

2016

jemds

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BACKGROUND AND OBJECTIVESOnychomycosis is an underreported progressive, recurrent fungal nail infection of human beings. So far, there is no documented study regarding causative agents of Onychomycosis in Tripura. In view of this, the study was conducted in a tertiary healthcare centre of Tripura aiming laboratory diagnosis of Onychomycosis with objectives of, (1) Epidemiology of Onychomycosis among the study subjects, (2) Profiling of aetiological agents.

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Section: Discussionmentioning

confidence: 99%

“…T. rubrum is generally linked to chronic dermatophytosis. [23] The virulence factors like keratinolytic enzymes (e.g. hydrolase, keratinase and cysteine dioxygenase) has been reported.…”

Section: Discussionmentioning

confidence: 99%

Clinico-Mycological Profile of Onychomycosis in a Tertiary Care Centre of Tripura

Debbarma¹,

Barman²,

Majumdar³

2016

jemds

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“…Die Bevölkerungs-Subpopulation der aschkenasischen Juden wird durch das humane Leukozyten-Antigen DR4 (HLA-DR4) vor einer Onychomykose geschützt [26]. HLA-DR6 fand sich bei 7 von 21 mexikanischen Mestizen mit Onychomykose (33 %), jedoch immerhin bei 45 % der Kontrollen [27].…”

Section: Genetische Disposition Für Eine Onychomykoseunclassified

Mykologie – ein Update. Teil 1: Dermatomykosen: Erreger, Epidemiologie und Pathogenese

Nenoff¹,

Krüger²,

Ginter‐Hanselmayer

et al. 2014

J Deutsche Derma Gesell

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“…Neben dem autosomal-dominanten Erbgang hat sich auch gezeigt, dass eine bestimmte Bevölkerungssubpopulation, die ashkenasischen Juden, durch das humane Leukozyten-Antigen DR4 (HLA-DR4) vor einer OM geschützt ist [38]. In einer prospektiven Fall-Kontroll-Studie wurde kürzlich dieser Zusammenhang zum HLA-DR4 bei mexikanischen Mestizen untersucht [2].…”

Section: Genetische Disposition Für Eine Onychomykoseunclassified

Onychomykose – ein Update

Nenoff¹,

Ginter‐Hanselmayer

Hj³

2011

Hautarzt

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Onychomycosis describes a chronic fungal infection of the nails most frequently caused by dermatophytes, primarily Trichophyton rubrum. In addition, yeasts (e. g. Candida parapsilosis), more rarely molds (Scopulariopsis brevicaulis), play a role as causative agents of onychomycosis. However, in every case it has to be decided if these yeasts and molds are contaminants, or if they are growing secondarily on pathological altered nails. The point prevalence of onychomycosis in Germany is 12.4%, as demonstrated within the "Foot-Check-Study", which was a part of the European Achilles project. Although, onychomycosis is rarely diagnosed in children and teens, now an increase of fungal nail infections has been observed in childhood. More and more, diabetes mellitus becomes important as significant disposing factor both for tinea pedis and onychomycosis. By implication, the onychomycosis represents an independent and important predictor for development of diabetic foot syndrome and foot ulcer. When considering onychomycosis, a number of infectious and non-infectious nail changes must be excluded. While psoriasis of the nails does not represent a specific risk factor for onychomycosis, yeasts and molds are increasing isolated from patients with psoriatic nail involvement. In most cases this represents secondary growth of fungi on psoriatic nails. Recently, stigmatization and impairment of quality of life due to the onychomycosis has been proven.

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HLA in Brazilian Ashkenazic Jews with chronic dermatophytosis caused by Trichophyton rubrum

Cited by 17 publications

References 21 publications

Clinico-Mycological Profile of Onychomycosis in a Tertiary Care Centre of Tripura

Clinico-Mycological Profile of Onychomycosis in a Tertiary Care Centre of Tripura

Mykologie – ein Update. Teil 1: Dermatomykosen: Erreger, Epidemiologie und Pathogenese

Onychomykose – ein Update

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