Synthesis and characterization of new methacrylate based hydrogels

Ferreira, Paula; Calvinho, Paulo; Cabrita, António Silvério; Schacht, Etienne; Gil, Maria Helena

doi:10.1590/s1516-93322006000300011

Cited by 6 publications

(3 citation statements)

References 17 publications

(12 reference statements)

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“…Even though TPA has been widely used for solid and semisolid food, recently it has attracted great attention in the characterization of pharmaceutical and polymeric systems. 52 Several mechanical parameters such as hardness, cohesiveness, springiness, and adhesiveness can be determined through TPA. 53 The representative force-time graphs of the CMCht-SF2:PEGDE1 scaffold is shown in Figure 8(d).…”

Section: Resultsmentioning

confidence: 99%

“…It was measured by the ratio of the up stroke energy and down stroke energy of the first compression (A 2–3 /A 1–2 ). 52–55 Accordingly, the obtained mechanical properties of the produced hydrogel scaffolds from TPA are given in Table 3. The hardness values of the samples increased with the cross-linker ratio as well as fiber incorporation.…”

Section: Resultsmentioning

confidence: 99%

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Wet-electrospun PHBV nanofiber reinforced carboxymethyl chitosan-silk hydrogel composite scaffolds for articular cartilage repair

et al. 2020

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The objective of the study was to produce three-dimensional and porous nanofiber reinforced hydrogel scaffolds that can mimic the hydrated composite structure of the cartilage extracellular matrix. In this regard, wet-electrospun poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) nanofiber reinforced carboxymethyl chitosan-silk fibroin (PNFs/CMCht-SF) hydrogel composite scaffolds that were chemically cross-linked by poly(ethylene glycol) diglycidyl ether (PEGDE) were produced. To the best of our knowledge, this is the first study in cartilage regeneration where a three dimensional porous spongy composite scaffold was obtained by the dispersion of wet-electrospun nanofibers within a polymer matrix. All of the produced hydrogel composite scaffolds had an interconnected microporous structure with well-integrated PHBV nanofibers on the pore walls. The scaffold comprising an equal amount of PEGDE and polymer (PNFs/CMCht-SF1:PEGDE1) demonstrated comparable water content (91.4 ± 0.7%), tan δ (0.183 at 1 Hz) and compressive strength (457 ± 85 kPa) values to that of articular cartilage. Besides, based on the histological analysis, this hydrogel composite scaffold supported the chondrogenic differentiation of bone marrow mesenchymal stem cells. Consequently, this hydrogel composite scaffold presented a great promise for cartilage tissue regeneration.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Wet-electrospun PHBV nanofiber reinforced carboxymethyl chitosan-silk hydrogel composite scaffolds for articular cartilage repair

et al. 2020

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“…Their rubberlike flexibility when they are hydrated (which minimizes the mechanical damage to surrounding tissues) and their low surface tension (which minimizes cell adsorption and adhesion) are their main advantages for such applications. 22 Acrylic and methacrylic monomers can be tailor-made for specific applications. By a change in the side chain, acrylic and methacrylic polymer polarity can be tuned within almost the entire polarity spectrum, from hydrophilic to hydrophobic.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and characterization of new methacrylate‐type hydrogels containing 2‐tert‐butylamino ethyl groups for sorption purposes

Bayramgil¹

2008

J of Applied Polymer Sci

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Crosslinked poly[2-(tert-butylamino)ethyl methacrylate] (PtBAEMA) hydrogels were synthesized by 60 Co-g-radiation-initiated simultaneous polymerization and crosslinking of 2-(tert-butylamino)ethyl methacrylate in bulk and in aqueous solutions. The results showed that the gelation percentage decreased with increasing water content. The structural and thermal characterizations of the hydrogels were accomplished with several techniques, including Fourier transform infrared spectroscopy, swelling measurements, thermogravimetry, and differential scanning calorimetry. The effects of time, pH, temperature, and ionic strength on the swelling behavior were also investigated. Swelling equilibrium was attained in 2-3 days. PtBAEMA hydrogels originally swelled to 350% (by volume) in deionized water, but this value reached 3000% around pH 2.0. PtBAEMA hydrogels were reversibly affected by the change in temperature within the temperature range of 4-708C. The swelling ratios of the gels decreased with increasing ionic strength. As a result, PtBAEMA hydrogels show stimuliresponsive properties depending on the characteristics of the environment, and they are being considered for adoption as some kind of carrying material for separation.

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Antibacterial Polypeptide nisin containing cotton modified hydrogel composite wound dressings

Güneş

Albayrak

2020

Polym. Bull.

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Synthesis and characterization of new methacrylate based hydrogels

Cited by 6 publications

References 17 publications

Wet-electrospun PHBV nanofiber reinforced carboxymethyl chitosan-silk hydrogel composite scaffolds for articular cartilage repair

Wet-electrospun PHBV nanofiber reinforced carboxymethyl chitosan-silk hydrogel composite scaffolds for articular cartilage repair

Synthesis and characterization of new methacrylate‐type hydrogels containing 2‐tert‐butylamino ethyl groups for sorption purposes

Antibacterial Polypeptide nisin containing cotton modified hydrogel composite wound dressings

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