2002
DOI: 10.1590/s1516-93322002000400010
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Saccharin analysis in pharmaceutical and cosmetic preparations by derivative ultraviolet spectrophotometry

Abstract: Saccharin, a synthetic sweetener constituent of several pharmaceutical and cosmetic preparations, is analyzed qualitatively and quantitatively in the presence of interferences like active ingredients and excipients. A derivative ultraviolet spectrophotometric method employing the second and the fourth orders was used. The calibration data obtained were satisfactory, with a relative precision range of 0.53%-0.72%, and linearity between 0.9998-0.9999. The recovery test results for the toothgel sample ranged betw… Show more

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Cited by 1 publication
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“…BATHINAPATLA ET AL. (Alghamdi, Alghamdi, and Alwarthan 2005;He, Fang, and Xu 2012;Vianna-Soares and Martins 2002). Therefore, the highly sensitive and specific determination of the sweetener in foods is an analytical challenge.…”
mentioning
confidence: 99%
“…BATHINAPATLA ET AL. (Alghamdi, Alghamdi, and Alwarthan 2005;He, Fang, and Xu 2012;Vianna-Soares and Martins 2002). Therefore, the highly sensitive and specific determination of the sweetener in foods is an analytical challenge.…”
mentioning
confidence: 99%