Evaluation of the haematology and biochemistry of Clarias gariepinus as biomakers of environmental pollution in Tiga dam, Nigeria

Abalaka, Samson Eneojo

doi:10.1590/s1516-89132013000300004

Cited by 25 publications

(19 citation statements)

References 19 publications

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“…Corroborating values of triglycerides were reported in Labeo rohita 21 . Abalaka 22 also reported low triglycerides values in Clarias gariepinus under wild conditions. It has been reported that constant energy demand leads to mobilization of triglycerides since they serve as lipid depots 18 , 23 .…”

Section: Resultsmentioning

confidence: 91%

Multiple biomarker responses (serum biochemistry, oxidative stress, genotoxicity and histopathology) in Channa punctatus exposed to heavy metal loaded waste water

Javed

Usmani

Ahmad

2017

Sci Rep

140

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Experiments were conducted to investigate the health of fish Channa punctatus inhabiting heavy metal-loaded waste water. Heavy metals in the order of Fe > Mn > Zn > Co > Ni > Cu = Cr were present in the waste water. Gills had high metal load followed by liver and then kidney. Albumin, albumin to globulin (A:G) ratio, triglyceride, high density lipoprotein (HDL) and very low density lipoprotein (VLDL) were found to be lower but phospholipid, low density lipoprotein (LDL), total protein, lipid and cholesterol were higher as compared to the reference. Oxidative stress markers such as superoxide dismutase (SOD), catalase (CAT), glutathione S transferase (GST) and lipid peroxidation (LPO) were significantly higher in all tissues, whereas reduced glutathione (GSH) levels were comparatively low. Damage to DNA was observed with significantly higher mean tail length of comets in the exposed fish gill cells (30.9 µm) followed by liver (24.3 µm) and kidney (20.6 µm) as compared to reference fish (5.2, 4.8 and 5.9 µm respectively). Histopathology in gill, liver and kidney also showed marked damage. Integrated biochemical, oxidative stress, genotoxicity and histopathological findings are valuable biomarkers for native fish adaptive patterns, and monitoring of water quality/pollution of freshwater ecosystems.

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Section: Resultsmentioning

confidence: 91%

Multiple biomarker responses (serum biochemistry, oxidative stress, genotoxicity and histopathology) in Channa punctatus exposed to heavy metal loaded waste water

Javed

Usmani

Ahmad

2017

Sci Rep

140

View full text Add to dashboard Cite

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“…The enzymes are important factors in assessing liver cytolysis and their existence in the serum might provide information on organ dysfunction (Ozer et al, 2008). Fish in a polluted aquatic system was reported to show high level of serum ALP, GOT and GPT, indicating tissue damage (Abalaka, 2013). In this study the levels of all these enzymes were found to be significantly lower (P<0.05) in fish fed plant extract supplemented diets compared to the control group (Table 6).…”

Section: Discussionmentioning

confidence: 53%

Dietary Administration of Ethanol and Methanol Extracts of Withania somnifera Root Stimulates Innate Immunity, Physiological Parameters and Growth in Nile Tilapia Oreochromis niloticus

Mukherjee¹,

Ghosal²,

Moniruzzaman³

et al. 2019

Croatian Journal of Fisheries

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Efficacy of ethanol and methanol extracts of medicinal herb Withania somnifera roots was evaluated in Nile tilapia Oreochromis niloticus on immunostimulation and growth. Withania roots were extracted with water, ethanol, methanol, methylene chloride, hexane, successive methanol. Phenol, flavonoid content and antiradical activity of all the extracts were measured. Ethanol extract showed the highest phenol, flavonoid content and antiradical activity followed by methanol extract. Subsequently, Nile tilapia (n = 126) were fed diets containing different concentrations (0.0, 0.3, 0.5 and 0.7 g kg−1 feed) of ethanol and methanol extracts of W. somnifera roots for 30 days (3 replicates). Fish fed plant extract fortified diets showed significantly better (P<0.05) immunological, haematological, biochemical and growth parameters compared to the fish fed control diet. Fish fed diet containing ethanol extract at the concentration of 0.7 g kg−1 feed showed the highest immunological (phagocytotic activity, respiratory burst activity, serum lysozyme, total protein, total immunoglobulin), haematological (total red blood cells, haemoglobin, hematocrit, total white blood cells, lymphocyte), biochemical (reduced glutathione, glutathione reductase activity) and growth (final weight, weight gain, daily weight gain, specific growth rate) parameters. The plant extract might act as potent free radical scavenger in fish tissues and have tissue protecting ability, thus increasing fish health.

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“…chemical changes which may be reflected in their tissues and blood components [8][9]. An increase of enzymes activity in the extracellular fluid or organs is a sensitive indicator of even minor cellular damage, since the levels of these enzymes within the cell may exceed those in the extracellular fluid by more than three orders of magnitude [10].…”

Section: * Corresponding Author Email: Nedieakani @ Yahoocom Phone Nmentioning

confidence: 99%

“…Gabriel et al [15] noted that increases or decreases in the values of ALT and AST indicate tissue damage in liver, kidney, muscle and gill. Alterations in alkaline phosphatase, ALP [16,17], lactate dehydrogenase, LDH [8,[18][19][20] and ALP activities in tissues, organs and serum have been reported in fish exposed to toxicants in varying concentrations and have been used as biomarker for tissue damage in fish and a good diagnostic tool in toxicological studies.…”

Section: * Corresponding Author Email: Nedieakani @ Yahoocom Phone Nmentioning

confidence: 99%

Enzymatic responses of Clarias gariepinus (Burchell, 1822) exposed to sub-lethal concentrations of an oilfield wastewater

Akani¹,

Gabriel²

2016

J App Biol Biotech

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Twenty eight adult Clarias gariepinus (mean weight 205 ± 12.89g SD; Mean length; 31.13 ± 3.82cm SD) were exposed to oilfield wastewater, oww (0. 10, 20, 30, 40, 50 and 60%) in quadruplicate for 28 days and the organs (plasma, gill, liver, kidney) and muscle were assayed for enzymes: aspartate transaminase (AST), alanine transaminase (ALT), acid phosphatase (ACP) alkaline phosphates (ALP) and lactate dehydrogenase (LDH). Changes in enzyme response were not concentration-dependent (P < 0.05), except ALP in kidney which showed a significant (p>0.05) increase with increased concentration of the oilfield wastewater when compared to the control. Other enzymes activities fluctuated around the control with LDH activity showing highest (2812.50±375.00 IU/L) response in all the organs. Lowest activity was recorded for ALT (4.00±0.00 IU/L) in the plasma. The changes observed can be used as an indicator of stress in C. gariepinus exposed to elevated levels of an oilfield wastewater. These changes can lead to death of fish and economic loss. The need therefore, for proper treatment of oilfield wastewater prior to discharge into the aquatic environment so as to reduce ecotoxicological problems and public health hazards is advocated.

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Evaluation of the haematology and biochemistry of Clarias gariepinus as biomakers of environmental pollution in Tiga dam, Nigeria

Abstract: This study aimed to evaluate the haematological and biochemical changes in

Cited by 25 publications

References 19 publications

Multiple biomarker responses (serum biochemistry, oxidative stress, genotoxicity and histopathology) in Channa punctatus exposed to heavy metal loaded waste water

Multiple biomarker responses (serum biochemistry, oxidative stress, genotoxicity and histopathology) in Channa punctatus exposed to heavy metal loaded waste water

Dietary Administration of Ethanol and Methanol Extracts of Withania somnifera Root Stimulates Innate Immunity, Physiological Parameters and Growth in Nile Tilapia Oreochromis niloticus

Enzymatic responses of Clarias gariepinus (Burchell, 1822) exposed to sub-lethal concentrations of an oilfield wastewater

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