Antibacterial activity of chitosan and the interpolyelectrolyte complexes of poly(acrylic acid)-chitosan

Ortega-Ortíz, Hortensia; Gutiérrez-Rodríguez, Baltazar; Cadenas‐Pliego, Gregorio; Jimenez, Luis Ibarra

doi:10.1590/s1516-89132010000300016

Cited by 31 publications

(18 citation statements)

References 21 publications

(19 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The structure of the MWCNTs, activated-MWCNTs, and CTSNPs-aMWCNTs were studied utilizing Fourier-transform infrared (FT-IR) spectroscopy as exhibited in Figure 2 e. Feature peaks at wave numbers 3275 cm −1 , 1643 cm −1 , and 1322 cm −1 equivalent to (–N–H, –O–H), (C=O), and (C–N), respectively, confirmed the realization of CTSNPs-aMWCNTs composites [ 34 , 35 ]. The peak with wave number 2940 cm −1 indicates the presence of C-H bonds, a dominating bond in Pristine-MWCNTs while peaks with wave numbers 1755 cm −1 , 3176 cm −1 , and 1113 cm −1 corresponding to (C=O), (-O-H), and (-C-O), respectively, suggest the carboxylation of the pristine-MWCNTs.…”

Section: Resultsmentioning

confidence: 99%

Detection of Quinoline in G. boninense-Infected Plants Using Functionalized Multi-Walled Carbon Nanotubes: A Field Study

Akanbi

Yusof

Abdullah

et al. 2017

Sensors

View full text Add to dashboard Cite

Carbon nanotubes (CNTs) reinforced with gold nanoparticles (AuNPs) and chitosan nanoparticles (CTSNPs) were anchored on a screen-printed electrode to fabricate a multi-walled structure for the detection of quinoline. The surface morphology of the nanocomposites and the modified electrode was examined by an ultra-high resolution field emission scanning electron microscope (FESEM), and Fourier-transform infrared (FT-IR) spectroscopy was used to confirm the presence of specific functional groups on the multi-walled carbon nanotubes MWCNTs. Cyclic voltammetry (CV) and linear sweep voltammetry (LSV) were used to monitor the layer-by-layer assembly of ultra-thin films of nanocomposites on the surface of the electrode and other electrochemical characterizations. Under optimized conditions, the novel sensor displayed outstanding electrochemical reactivity towards the electro-oxidation of quinoline. The linear range was fixed between 0.0004 and 1.0 μM, with a limit of detection (LOD) of 3.75 nM. The fabricated electrode exhibited high stability with excellent sensitivity and selectivity, specifically attributable to the salient characteristics of AuNPs, CTSNPs, and MWCNTs and the synergistic inter-relationship between them. The newly developed electrode was tested in the field. The Ipa increased with an increase in the amount of quinoline solution added, and the peak potential deviated minimally, depicting the real capability of the newly fabricated electrode.

show abstract

Section: Resultsmentioning

confidence: 99%

Detection of Quinoline in G. boninense-Infected Plants Using Functionalized Multi-Walled Carbon Nanotubes: A Field Study

Akanbi

Yusof

Abdullah

et al. 2017

Sensors

View full text Add to dashboard Cite

show abstract

“…Chitosan has excellent biocompatibility and biodegradability, being a nontoxic natural biological material. It can interact with negatively charged proteins and polymers because of its positive charges and the ─NH 2 group terminals and has, therefore, been widely used in the pharmaceutical industry in recent years (Ortega‐Ortiz, Gutiérrez‐Rodríguez, Cadenas‐Pliego, & Ibarra Jimenez, ; Venkatesan & Kim, ). BMP‐2 was shown to be continuously released for up to 6 weeks from a silica xerogel–chitosan hybrid coating layer on a porous HA scaffold and promoted the repair of bone defects (Jun et al, ).…”

Section: Discussionmentioning

confidence: 99%

Effects of a bone graft substitute consisting of porous gradient HA/ZrO₂and gelatin/chitosan slow‐release hydrogel containing BMP‐2 and BMSCs on lumbar vertebral defect repair in rhesus monkey

Shao

Quan

Wang

et al. 2017

J Tissue Eng Regen Med

View full text Add to dashboard Cite

Dense biomaterial plays an important role in bone replacement. However, it fails to induce bone cell migration into graft material. In the present study, a novel bone graft substitute (BGS) consisting of porous gradient hydroxyapatite/zirconia composite (PGHC) and gelatin/chitosan slow-release hydrogel containing bone morphogenetic protein 2 and bone mesenchymal stem cells was designed and prepared to repair lumbar vertebral defects. The morphological characteristics of the BGS evaluated by a scanning electron microscope showed that it had a three-dimensional network structure with uniformly distributed chitosan microspheres on the surfaces of the graft material and the interior of the pores. Then, BGS (Group A), PGHC (Group B), or autologous bone (Group C) was implanted into lumbar vertebral body defects in a total of 24 healthy rhesus monkeys. After 8 and 16 weeks, anteroposterior and lateral radiographs of the lumbar spine, microcomputed tomography, histomorphometry, biomechanical testing, and biochemical testing for bone matrix markers, including Type I collagen, osteocalcin, osteopontin, basic fibroblast growth factor, alkaline phosphatase, and vascular endothelial growth factor, were performed to examine the reparative efficacy of the BGS and PGHC. The BGS displayed excellent ability to repair the lumbar vertebral defect in rhesus monkeys. Radiography, microcomputed tomography scanning, and histomorphological characterization showed that the newly formed bone volume in the interior of the pores in the BGS was significantly higher than in the PGHC. The results of biomechanical testing indicated that the vertebral body compression strength of the PGHC implant was lower than the other implants. Reverse-transcription polymerase chain reaction and western blot analyses showed that the expression of bone-related proteins in the BGS implant was significantly higher than in the PGHC implant. The BGS displayed reparative effects similar to autologous bone. Therefore, BGS use in vertebral bone defect repair appears promising.

show abstract

“…Once inside the cell, where the pH is maintained near 7, the acid will dissociate and pH will decrease, thus disturbing and finally killing the microorganism (31) . The secondary action is the anionic part of the organic acids (carboxylic groups) that cannot escape the bacteria in its dissociated form will accumulate within the bacteria and disrupt many metabolic functions, leading to osmotic pressure increase, incompatible with the survival of the bacteria (32)(33)(34) .…”

Section: Inhibition Mechanism Of Chitosan Solutionsmentioning

confidence: 99%

A Study on The Effect of Type of Solvent on Chitosan Efficiency for Treatment of Drinking Water Contaminations

2014

Egypt. J. Chem.

View full text Add to dashboard Cite

N this research, chitosan (Ch) a natural polymer, was employed in drinking raw water treatment of Nile River against Escherichia coli via simple method, it is dissolution of chitosan in three different solvents;acetic acid (AC),malonic acid (MA) and N carboxymethyl N,N diethylbenzene ammonium chloride (CMEBAC) to produce three different solutions; Ch-AC, Ch-MA and Ch-CMEBAC, respectively. These solutions were characterized by FTIR and elemental analysis. The investigations of their effect against total coliform bacteria of raw water were carried out according to method of Most Probable Number (MPN) at different contact times (30, 60 and 120 min). The results showed that the full inhibition of total coliform were achieved after 30 min as contact time by 7 gm L -1 ml of Ch-Ac , 5 gm L -1 of Ch-Ma and 0.75 gm L -1 ml of Ch-CMEBAC. Otherwise, by increasing of contact time, the volumes of inhibitors (chitosan solutions) decrease.The minimum inhibitory concentration (MIC) values of those solutions were detected as 2.75, 2 and 0.2 µ/ml , respectively.

show abstract

Antibacterial activity of chitosan and the interpolyelectrolyte complexes of poly(acrylic acid)-chitosan

Abstract: ABSTRACT

Cited by 31 publications

References 21 publications

Detection of Quinoline in G. boninense-Infected Plants Using Functionalized Multi-Walled Carbon Nanotubes: A Field Study

Detection of Quinoline in G. boninense-Infected Plants Using Functionalized Multi-Walled Carbon Nanotubes: A Field Study

Effects of a bone graft substitute consisting of porous gradient HA/ZrO₂and gelatin/chitosan slow‐release hydrogel containing BMP‐2 and BMSCs on lumbar vertebral defect repair in rhesus monkey

A Study on The Effect of Type of Solvent on Chitosan Efficiency for Treatment of Drinking Water Contaminations

Contact Info

Product

Resources

About

Antibacterial activity of chitosan and the interpolyelectrolyte complexes of poly(acrylic acid)-chitosan

Abstract: ABSTRACT

Cited by 31 publications

References 21 publications

Detection of Quinoline in G. boninense-Infected Plants Using Functionalized Multi-Walled Carbon Nanotubes: A Field Study

Detection of Quinoline in G. boninense-Infected Plants Using Functionalized Multi-Walled Carbon Nanotubes: A Field Study

Effects of a bone graft substitute consisting of porous gradient HA/ZrO2and gelatin/chitosan slow‐release hydrogel containing BMP‐2 and BMSCs on lumbar vertebral defect repair in rhesus monkey

A Study on The Effect of Type of Solvent on Chitosan Efficiency for Treatment of Drinking Water Contaminations

Contact Info

Product

Resources

About

Effects of a bone graft substitute consisting of porous gradient HA/ZrO₂and gelatin/chitosan slow‐release hydrogel containing BMP‐2 and BMSCs on lumbar vertebral defect repair in rhesus monkey