Calculation of fermentation parameters from the results of a fed-batch test taking account of the volume of biomass in the fermenting medium

Borzani, Walter

doi:10.1590/s1516-89132008000300001

Cited by 4 publications

(2 citation statements)

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“…The final time t f and the feed stream Q are determined in order to meet the biochemical (7), control (8) and terminal constrains (6) and maximize the FOS concentration. The optimization control problem is solved for three different cases, namely: The results are given in Table 3 where the yield Y(t f ) is now defined by [36]…”

Section: Results For the Fed-batch Casementioning

confidence: 99%

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Optimal control for fermentative production of fructo-oligosaccharides in fed-batch bioreactor

Schorsch

Castro

Couto

et al. 2019

Journal of Process Control

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The production of high-content fructo-oligosaccharides by fermentation in a fed-batch bioreactor is considered. Fed-batch scenario allows to reduce inhibition mechanisms caused by the presence of byproducts, such as glucose, while maximizing biomass production. The determination of the feed flow rate profile that maximizes the concentration of fructo-oligosaccharides is performed by resorting to the maximum principle of Pontryagin. The optimization procedure takes into account inequality constraints on the state and control variables and allows the determination of the unspecified final fermentation time corresponding to maximal fructo-oligosaccharides content. The performance of the approach is demonstrated by simulations in the case of fructo-oligosaccharide production by Aspergillus sp.

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Section: Results For the Fed-batch Casementioning

confidence: 99%

“…Fed-batch 1 Fed-batch 2 Fed-batch 3 6.8 g L −1 h −1 and Y(t f,batch ) = 61.78%. The latter two are given by the following equations [36]…”

Section: Batchmentioning

confidence: 99%