Deficiência de ferro no paciente submetido à ressecção gástrica ou intestinal: prevalência, causas, repercussões clínicas, abordagem diagnóstica e prevenção

Traina, Fabı́ola

doi:10.1590/s1516-84842010005000071

Cited by 8 publications

(6 citation statements)

References 39 publications

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“…Treatment with IV iron in some clinical situations could present some advantages over oral iron, such as faster and higher increases of hemoglobin (Hb) levels and body iron stores. 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 …”

Section: Intravenous Iron Therapymentioning

confidence: 99%

Intravenous ferric carboxymaltose for the treatment of iron deficiency anemia

Friedrisch

Cançado

2015

Revista Brasileira de Hematologia e Hemoterapia

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Nutritional iron deficiency anemia is the most common deficiency disorder, affecting more than two billion people worldwide. Oral iron supplementation is usually the first choice for the treatment of iron deficiency anemia, but in many conditions, oral iron is less than ideal mainly because of gastrointestinal adverse events and the long course needed to treat the disease and replenish body iron stores. Intravenous iron compounds consist of an iron oxyhydroxide core, which is surrounded by a carbohydrate shell made of polymers such as dextran, sucrose or gluconate. The first iron product for intravenous use was the high molecular weight iron dextran. However, dextran-containing intravenous iron preparations are associated with an elevated risk of anaphylactic reactions, which made physicians reluctant to use intravenous iron for the treatment of iron deficiency anemia over many years. Intravenous ferric carboxymaltose is a stable complex with the advantage of being non-dextran-containing and a very low immunogenic potential and therefore not predisposed to anaphylactic reactions. Its properties permit the administration of large doses (15 mg/kg; maximum of 1000 mg/infusion) in a single and rapid session (15-minute infusion) without the requirement of a test dose. The purpose of this review is to discuss some pertinent issues in relation to the history, pharmacology, administration, efficacy, and safety profile of ferric carboxymaltose in the treatment of patients with iron deficiency anemia.

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Section: Intravenous Iron Therapymentioning

confidence: 99%

Intravenous ferric carboxymaltose for the treatment of iron deficiency anemia

Friedrisch

Cançado

2015

Revista Brasileira de Hematologia e Hemoterapia

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“…Among the complications has been the early and late ones, and within these two categories can find many clinical situations already exhaustively related 5 , 11 . Associated with metabolic complications are those of psychological origin 3 , 26 .…”

Section: Discussionmentioning

confidence: 99%

Proposal of a Revisional Surgery to Treat Severe Nutritional Deficiency Post-Gastric Bypass

Sampaio-Neto

Branco-Filho

Nassif

et al. 2016

ABCD, arq. bras. cir. dig.

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Background The gastric bypass has nutritional and electrolyte disturbances rate of approximately 17%. The most common deficits are protein malnutrition, ferric and zinc, in addition to the vitamin. Although rare, some malnutrition stages reach such severity that ends up being necessary hospitalization and sometimes revisional or reversal surgical procedures.Aim: To present a proposal of surgical revision for treatment of severe malnutrition after bariatric surgery.Methods: The procedure is to reconstitute the food transit through the duodenum and proximal jejunum, keeping the gastric bypass restrictive component. As an additional strategy, the gastric fundus resection is performed, aiming to intensify the suppression of the greline and avoiding excessive weight regain.Results: After initial stabilization, nutritional and electrolytic support, the procedure was performed in two patients as definitive treatment of malnutrition status. Good results were observed at one year follow up.Conclusion: As improvement option and/or resolution of the nutritional alterations, surgical therapy is one of the alternatives. There is still no consensus on the surgical technique to be performed. This procedure is based on pathophysiological factors for the treatment of this condition, with good initial results, without significant clinical alterations. Longer follow-up will determine its effectiveness.

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“…Contudo, podem ocorrer também intolerâncias alimentares no pós-operatório 13 . Alguns autores (Silva et al, Carvalho et al, Costa et al, Eltweri et al, Traina et al, Schweiger et al, Moreira et al) 12,16,19,21,[36][37][38] relatam em seus estudos sobre pacientes submetidos à cirurgia bariátrica que a carne vermelha foi o principal alimento responsável por essas intolerâncias, podendo, assim, explicar a deficiência da cobalamina, já que esta é disponibilizada em alimentos de origem animal e sua absorção no íleo depende da presença de fator intrínseco liberado pelas células parietais do estômago 16,35 .…”

Section: Conclusãounclassified

Deficiência De Vitamina B12 No Pós-Operatório De Cirurgia Bariátrica: Uma Revisão De Literatura

Dourado¹,

Paula²

2018

rsc

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This article discusses vitamin B12 deficiency and its reflexes in the health of people undergoing bariatric surgery. This is an exploratory descriptive study of the type literature review in which a search was conducted for articles from journals indexed in the Pubmed/MEDLINE and Scielo databases, using the descriptors bariatric surgery, obesity, postoperative care, malnutrition and vitamin B12 in order to gather information about this deficiency and its reflexes on the health of this population. The inclusion criteria were work on the theme from 2005 to 2016. With this, 35 articles were selected. The findings confirmed the existence of malnutrition of vitamin B12 in people who underwent this type of surgery and explained the importance of its longterm supplementation for its prevention and/or treatment, and although there are no specific recommendations for this population yet, it has been a preventive clinical practice to administer 1000 μg parenteral in the preoperative period and in the postoperative period may be oral (2000 mcg/120 days) or intramuscular (1000 mcg injections). Therefore, this deficiency in bariatric patients is evidenced in the current literature that elucidates their health reflexes, demonstrating the importance of their supplementation before and after surgery, but there is a need for more specific studies that help in the creation of precise protocols.

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Deficiência de ferro no paciente submetido à ressecção gástrica ou intestinal: prevalência, causas, repercussões clínicas, abordagem diagnóstica e prevenção

Cited by 8 publications

References 39 publications

Intravenous ferric carboxymaltose for the treatment of iron deficiency anemia

Intravenous ferric carboxymaltose for the treatment of iron deficiency anemia

Proposal of a Revisional Surgery to Treat Severe Nutritional Deficiency Post-Gastric Bypass

Deficiência De Vitamina B12 No Pós-Operatório De Cirurgia Bariátrica: Uma Revisão De Literatura

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