Deficiência de ferro no paciente com câncer

Calabrich, Aknar; Katz, Artur

doi:10.1590/s1516-84842010005000049

Cited by 6 publications

(7 citation statements)

References 22 publications

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“…Recombinant human EPO (rhuEPO) is often used in chronic renal patients with acquired immune deficiency syndrome and/or cancer. Anemia is a frequent complication in cancer patients 27 . Up to 70% of these patients present anemia at some stage of their disease or treatment.…”

Section: Drugs Adjuvant In Cancer Treatmentmentioning

confidence: 99%

“…Anemia can be one of the early signs of neoplastic disease, but is more commonly associated with antineoplastic treatment or disease progression. The incidence and severity of anemia depend on the type of tumor, patient's age, disease stage, and type and intensity of antineoplastic treatment 27 . A consensus elaborated by the American Society of Clinical Oncology and American Society of Hematology recommends the use of rhuEPO in patients with hemoglobin < 10 g/dL, whereas for those with hemoglobin between 10 and 12 g/dL, the decision should be determined by clinical circumstances 28 .…”

Section: Drugs Adjuvant In Cancer Treatmentmentioning

confidence: 99%

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Hypertension in Patients with Cancer

Souza¹,

Silva²,

Ribeiro³

et al. 2015

Arquivos Brasileiros De Cardiologia

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There is a known association between chemotherapy and radiotherapy for treatment of cancer patients and development or worsening of hypertension. The aim of this article is to review this association. A literature search was conducted for articles reporting this association on the databases PubMed, SciELO and LILACS between 1993 and 2013. There was a high coprevalence of hypertension and cancer, since both diseases share the same risk factors, such as sedentary lifestyle, obesity, smoking, unhealthy diet and alcohol abuse. The use of chemotherapy and adjuvant drugs effective in the treatment of cancer increased the survival rate of these patients and, consequently, increased the incidence of hypertension. We described the association between the use of angiogenesis inhibitors (bevacizumab, sorafenib and sunitinib), corticosteroids, erythropoietin and non-steroidal anti-inflammatory drugs with the development of hypertension. We also described the relationship between hypertension and carotid baroreceptor injury secondary to cervical radiotherapy. Morbidity and mortality increased in patients with cancer and hypertension without proper antihypertensive treatment. We concluded that there is need for early diagnosis, effective monitoring and treatment strategies for hypertension in cancer patients in order to reduce cardiovascular morbidity and mortality.

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Section: Drugs Adjuvant In Cancer Treatmentmentioning

confidence: 99%

Section: Drugs Adjuvant In Cancer Treatmentmentioning

confidence: 99%

Hypertension in Patients with Cancer

Souza¹,

Silva²,

Ribeiro³

et al. 2015

Arquivos Brasileiros De Cardiologia

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“…Outro sintoma que demonstrou destaque nesta pesquisa foi a dispneia. Tal sintoma pode correlacionar--se com a diminuição dos níveis de hemoglobina, o que impacta negativamente a sobrevida e acentua a FRC 31 . O termo dispneia é utilizado para definir uma sensação subjetiva de falta de ar ou dificuldade respiratória que o doente diz sentir, sendo um dos sintomas mais prevalentes em diversos estudos, ocorrendo entre 19% e 51% dos doentes oncológicos, e rapidamente aumenta com a progressão da doença e no fim de vida, especialmente em doentes com câncer de pulmão 32 .…”

Section: Discussionunclassified

Cluster de Sintomas e o Impacto na Qualidade de Saúde Global de Pacientes com Câncer Avançado

Mello

Guimarães

Monteiro

et al. 2021

Rev. Bras. Cancerol.

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Introdução: Os pacientes com câncer podem apresentar múltiplos sintomas que se inter-relacionam, formando os chamados clusters ou agrupamentos de sintomas. Objetivo: Avaliar a relação entre um cluster de sintomas e a qualidade de saúde global de pacientes com câncer avançado. Método: Estudo analítico, transversal, com 146 pacientes. Foram utilizados instrumentos de caracterização sociodemográficas e de avaliação de qualidade de vida. Para analise dos dados, aplicaram-se os testes Kolmogorov-Smirnov, Mann-Whitney e Kruskal-Wallis. A coleta de dados foi realizada entre julho de 2019 e fevereiro de 2020 e utilizado o questionário 30-item European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30), versão 3. Resultados: A correlação de Spearman mostrou-se positiva entre o escore final da escala de sintomas e o escore final da avaliação global da saúde (ρ=0,605; p<0,001). Além disso, observou-se que o incremento de 1 ponto na pergunta: “Precisou descansar?” associou-se com aumento de 5,87 pontos no escore da qualidade da saúde global (p<0,01); para a pergunta “Sentiu-se cansado/a?”, 6,14 pontos (p<0,01); e “Teve falta de ar?”, 5,08 pontos (p<0,01). Conclusão: Existe uma correlação positiva entre o cluster de sintomas composto por dor, fadiga, dispneia, náusea, vomito, insônia, inapetência, constipação, diarreia e a qualidade de saúde global de pacientes com câncer.

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“…It is one of the most common clinical syndromes in clinical practice and in hospitalized patients. In this case it was caused by the cancer or by the infection originated from the myiasis, characterized by the decreased survival of red blood cells, failure of the bone marrow to increase red blood cell production and disorder of the deposit iron mobilization of the phagocytic mononuclear system 23 .…”

Section: Discussionmentioning

confidence: 99%

Myiasis associated with an invasive ductal carcinoma of the left breast: case study

Rodrigues

Klemig

Cardozo

et al. 2017

Rev. Inst. Med. trop. S. Paulo

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Most breast cancers originate in the ductal epithelium and are referred to as invasive ductal carcinoma. In this study we report on the clinical procedures adopted to diagnose myiasis in association with infiltrating metastatic breast carcinoma in a female patient. A 41 years old woman came to the Federal Hospital of Andaraí complaining of intense itching, warmth, redness and hardening of the breast, which had acquired the aspect of an orange peel. A lesion in the left breast was cavitated, dimpled, had fetid odor, and had fibrotic and infected air nodules filled with exudate and Dipteran larvae. The tissue was cleaned and 33 larvae were extracted. The patient was hospitalized and received Ivermectin. Eighteen of the larvae extracted from the patient were placed in 70% alcohol, and twelve were placed in a container with sterile wood shavings under controlled conditions until they metamorphosed into adults. The taxonomic identification of the flies revealed that the culprit was Cochliomyia hominivorax. A histopathological exam conducted three months earlier had revealed infiltrating ductal carcinoma. Two months after the myiasis treatment, the breast tissue had healed. The patient had waited ten days from the onset of the myiasis to seek treatment, and that delay interfered negatively in the prognosis of both the neoplasm and the myiasis. This study is relevant to public health in view of the strong social impact of myiasis.

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Deficiência de ferro no paciente com câncer

Cited by 6 publications

References 22 publications

Hypertension in Patients with Cancer

Hypertension in Patients with Cancer

Cluster de Sintomas e o Impacto na Qualidade de Saúde Global de Pacientes com Câncer Avançado

Myiasis associated with an invasive ductal carcinoma of the left breast: case study

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