Infecção pelo vírus da hepatite B em hemofílicos em Goiás: soroprevalência, fatores de risco associados e resposta vacinal

Tavares, Renato; Barbosa, Adriana P.; Teles, Sheila Araújo; Carneiro, Megmar Aparecida dos Santos; Lopes, Carmen Luci Rodrigues; Silva, Simonne A.; Yoshida, Clara Fumiko Tachibana; Martins, Regina Maria Bringel

doi:10.1590/s1516-84842004000300007

Cited by 1 publication

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References 38 publications

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“…(2) HBV can be transmitted through contaminated blood or other bodily fluids, via percutaneous or mucosal exposure. (3) As such, children born from women infected with hepatitis B, (4,5) individuals who have received multiple blood transfusions, (6) drug users, (7,8) and individuals with multiple sexual partners (9) are considered to be high risk groups for HBV infection. …”

Section: Introductionmentioning

confidence: 99%

Epidemiology of hepatitis B virus infection in first-time blood donors in the southwestern region of Goiás, central Brazil

Anjos

Martins

Carneiro

et al. 2010

Rev. Bras. Hematol. Hemoter.

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Introduction Little is known about the epidemiology of hepatitis B virus (HBV) infection in populations from inner cities, especially in Central Brazil. Thus the objective of this study was to estimate the prevalence of HBV infection, and to analyze the factors associated with HBV infection, in a population of first-time blood donors in the southwestern region of Goiás, Central Brazil. Methods A total of 984 individuals were interviewed and gave blood samples to detect serological markers of HBV (HBsAg, anti-HBs, and anti-HBc) by enzyme linked immunosorbent assays. Results An overall prevalence of 6.9% was found for HBV, with constituent prevalence rates of 3.6% and 11.6%, in subjects classified as fit and unfit to donate blood according the epidemiological screening, respectively. Only three individuals were positive for anti-HBs alone, suggesting previous vaccination against HBV. The variables of prior blood transfusion (OR = 2.3), tattoo/piercing (OR = 2.1), illicit drug use (OR = 2.3), sex with a partner with hepatitis (OR = 14.7), and history of sexually transmitted diseases (OR = 2.9) were independently associated with HBV-positivity. These data suggested a low endemicity of hepatitis B in the studied population. Conclusion The findings of low hepatitis B immunization coverage and the association of hepatitis B with risky behavior highlight that there is a need to intensify hepatitis B prevention programs in the southwest region of Goiás.

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