Estudo da refratariedade plaquetária em pacientes submetidos ao transplante de medula óssea do dia 0 ao dia + 50

Abstract

Resumo de Tese / Thesis Estudo da refratariedade plaquetária em pacientes submetidos ao transplante de medula óssea do dia 0 ao dia + 50

Comments on: frequency of human platelet antigens in oncohematological patients with thrombocytopenia and the probability of incompatibility to platelet transfusions

“…The frequency of this complication in oncohematological patients varies depending on the study; in a recent analysis of the TRAP (Trial to Reduce Alloimmunization to Platelets) Study, platelet refractoriness developed in 27% of patients with acute leukemia ( 5 ) . In Brazil, a single center study published in 2004 describes an extremely high frequency, with 80% of patients developing this complication in the early phase of hematopoietic stem cell transplantation ( 6 ) . However, in a more recent study, a 19% frequency of platelet refractoriness, much closer to data of several other studies, was demonstrated among oncohematological patients ( 7 ) .…”