A review on predictors of treatment outcome in social anxiety disorder

Mululo, Sara Costa Cabral; Menezes, Gabriela Bezerra de; Vigne, Paula; Fontenelle, Leonardo F.

doi:10.1590/s1516-44462012000100016

Cited by 41 publications

(18 citation statements)

References 35 publications

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“…The degree of comorbidity remained a significant predictor of (more) symptom severity (LSAS score at treatment end) over and above the effects of symptom severity at the beginning of treatment (initial LSAS score); it also indicated a lower probability to achieve response (but not remission). As the variable ‘number of comorbid mental diagnoses’ combined other axis I and axis II diagnoses, this finding replicates in part some previous studies (Lincoln et al, ; Mululo et al, ). It is of note, however, that the incremental effects were rather small (see also Olatunji, Cisler & Tolin, ).…”

Section: Discussionsupporting

confidence: 88%

“…The studies differ with respect to which variables were investigated. In the majority of studies, only a limited range of predictors was considered (refer to Lincoln et al, 2005 andMululo, De Menezes, Vigne, &Fontenelle, 2012 for overviews). Socio-demographic variables such as age, gender, marital status, education and occupation are typically unrelated to outcome.…”

mentioning

confidence: 99%

“…Socio-demographic variables such as age, gender, marital status, education and occupation are typically unrelated to outcome. Severity of disorder, generalised subtype, comorbid axis I disorder (e.g., depression) and comorbid axis II disorder (e.g., avoidant personality disorder) are associated with worse response in most studies, although their results require replication (Lincoln et al, 2005;Mululo et al, 2012). Positive treatment expectations and homework compliance have been related to change and high end state but were investigated only in a few studies (Lincoln et al, 2005;Mululo et al, 2012); however, across different disorders (e.g., depression), those variables were found to impact treatment success in a similar manner (e.g., Tsai, Ogrodniczuk, Sichting, & Mirmiran, 2014).…”

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confidence: 99%

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Baseline Patient Characteristics Predicting Outcome and Attrition in Cognitive Therapy for Social Phobia: Results from a Large Multicentre Trial

Hoyer

Wiltink

Hiller

et al. 2014

Clin Psychology and Psychoth

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Personality, self-esteem, shame, attachment style and interpersonal problems do not or only marginally moderate the effects of interventions in CT of social phobia. Symptom severity and comorbid diagnoses might affect treatment outcome negatively. Beyond these two factors, most patients share a similar likelihood of treatment success when treated according to the manual by Clark and Wells. Copyright © 2014 John Wiley & Sons, Ltd.

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Section: Discussionsupporting

confidence: 88%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Baseline Patient Characteristics Predicting Outcome and Attrition in Cognitive Therapy for Social Phobia: Results from a Large Multicentre Trial

Hoyer

Wiltink

Hiller

et al. 2014

Clin Psychology and Psychoth

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“…Numerous studies have investigated predictors of outcome of psychological treatments for SAD (e.g., Craske et al, 2014; Mululo, Menezes, Vigne, & Fontenelle, 2012). However, only a few studies have identified baseline predictors of pharmacotherapy outcomes.…”

Section: Introductionmentioning

confidence: 99%

Pharmacotherapy for social anxiety disorder: Interpersonal predictors of outcome and the mediating role of the working alliance

Cohen

Drabick

Blanco

et al. 2017

Journal of Anxiety Disorders

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Social anxiety disorder (SAD) is highly prevalent and associated with high levels of impairment and distress. Therapies for SAD leave many patients symptomatic at the end of treatment, and little is known about predictors or mechanisms of treatment outcome. Given the interpersonal dysfunction fundamental to SAD, this study investigated whether prominent interpersonal features of SAD (submissive behavior, childhood maltreatment, suppression of anger, and depression) predicted attrition and response to pharmacotherapy and whether the working alliance mediated these relationships. This is the first study to examine the role of the working alliance in pharmacotherapy for SAD. One hundred thirty-eight treatment-seeking individuals with a primary diagnosis of SAD received 12 weeks of open treatment with paroxetine. Higher levels of depression predicted greater severity of SAD at the end of treatment, and higher levels of submissive behavior and childhood emotional maltreatment predicted a greater probability of attrition from treatment. The psychiatrist-assessed working alliance mediated response to pharmacotherapy for individuals who reported a history of emotional maltreatment. These results identify variables that predict pharmacotherapy outcome and emphasize the importance of the working alliance as a mechanism of treatment response for those with a history of emotional maltreatment. Implications for person-specific treatment selection are discussed.

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“…Nesse sentido, é correto afirmar que a ansiedade patológica está associada a baixos níveis de qualidade de vida, bem como a notórias deficiências sociais, educacionais e ocupacionais (MULULO et al, 2012). A desordem da ansiedade é considerada a doença mental mais comum em todo o mundo, sendo o diagnóstico psiquiátrico mais corrente em todo o globo, afligindo entre 10-30% da população (BADGUJAR;SURANA, 2010;NETTO et al, 2009).…”

Section: Resultsunclassified

Ansiedade: aspectos gerais e tratamento com enfoque nas plantas com potencial ansiolítico

Sousa¹,

Oliveira²,

Calou³

2018

REVINTER

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ResumoEstima-se que 10-30% da população mundial sofra de ansiedade. Essa doença se manifesta por sensações de mal-estar psíquico, traduzidos por uma variedade de perturbações somáticas relacionadas à hiperatividade autonômica. Neste contexto, o objetivo deste trabalho foi realizar uma revisão bibliográfica sobre os aspectos mais relevantes da ansiedade, dos seus tratamentos e das perspectivas de abordagens terapêuticas advindas das plantas medicinais. A indústria farmacêutica dispõe de um grande arsenal terapêutico para a ansiedade, não obstante, sua maioria é constituída por fármacos que atuam de forma poderosa sobre o Sistema Nervoso Central, gerando inúmeros efeitos adversos em seus usuários. Dessa forma, a busca por alternativas mais seguras e efetivas encontra nas plantas medicinais uma fonte promissora, sendo grande a variedade de plantas usadas com esse propósito, onde a maioria delas já passou por testes pré-clínicos, no entanto, estes devem ser complementados com testes clínicos a fim de atestar a segurança e a eficácia das mesmas. Foi percebido que a maioria das ervas medicinais devidamente testadas podem servir como alternativas aos ansiolíticos tradicionais em pacientes que não conseguem adesão à terapia convencional, entretanto, merecem destaque a Piper methysticum G. Forster e as plantas do genêro Passiflora, sendo essas bastante utilizadas e de eficácia comprovada, logo, a bioprospecção molecular objetivando a descoberta de novas drogas ansiolíticas tem ganhado impulso uma vez que a busca por terapias alternativas e/ou complementares está em franca ascensão por aqueles que padecem de desordens do humor e de ansiedade. Palavras-chave: Plantas medicinais. Propriedades ansiolíticas. Testes da atividade ansiolítica. Anxiety: general aspects and treatment with focus on plants with anxiolytic potential AbstractIt is estimated that 10-30% of the world population suffering from anxiety. This disease cause feelings of psychic malaise, translated by a variety of somatic disorders related to autonomic hyperactivity. In this context, the aim of this study was to perform a literature review of the most relevant aspects of anxiety, treatments and the prospects for therapeutic approaches arising from medicinal plants. There many drugs aimed at treating anxiety, however, are mostly

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A review on predictors of treatment outcome in social anxiety disorder

Cited by 41 publications

References 35 publications

Baseline Patient Characteristics Predicting Outcome and Attrition in Cognitive Therapy for Social Phobia: Results from a Large Multicentre Trial

Baseline Patient Characteristics Predicting Outcome and Attrition in Cognitive Therapy for Social Phobia: Results from a Large Multicentre Trial

Pharmacotherapy for social anxiety disorder: Interpersonal predictors of outcome and the mediating role of the working alliance

Ansiedade: aspectos gerais e tratamento com enfoque nas plantas com potencial ansiolítico

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