The influence of the comorbidity between depression and alcohol use disorder on suicidal behaviors in the São Paulo Epidemiologic Catchment Area Study, Brazil

Coêlho, Bruno Mendonça; Andrade, Laura Helena; Guarniero, Francisco Bevilacqua; Wang, Yuan‐Pang

doi:10.1590/s1516-44462010005000027

Cited by 13 publications

(8 citation statements)

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“…Similar results were obtained previously by other researchers. It was shown that alcohol consumption increases the risk of developing depression [ 34 , 35 ]. Also, sedentary lifestyle (physical inactivity) and obesity are associated with the prevalence of DSs [ 36 , 37 ].…”

Section: Discussionmentioning

confidence: 99%

Depressive symptoms in patients diagnosed with benign prostatic hyperplasia

Pietrzyk

Olszanecka-Glinianowicz

Owczarek

et al. 2015

Int Urol Nephrol

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BackgroundSymptoms of depression are common in patients diagnosed with benign prostatic hyperplasia (BPH) and are usually a reaction to deterioration of health, severity of lower urinary tract symptoms, and erectile dysfunction. The aim of this observational study was to evaluate the prevalence of depressive symptoms in patients diagnosed with BPH and factors affecting their occurrence in a large Polish cohort.Patients and methodsFour thousand thirty-five men (4,035) diagnosed with BPH participated in the survey (age 65 ± 8 years). The occurrence of symptoms of depression was assessed using the Beck depression inventory, severity of lower urinary tract symptoms (LUTS) on the basis of the international prostate symptoms score, and erectile dysfunction using the international index of erectile function (IIEF-5).ResultsDepressive symptoms were found in 22.4 % of patients (mild in 20.8 % and moderate/severe in 1.6 %). Erectile dysfunction was found in 71.9 % of patients. Monotherapy for BPH was prescribed to 50.9 % of patients (mostly ARA—selective α1-selective alpha-adrenolytic—47.5 %), while polytherapy (ARA with a 5-alpha reductase inhibitor—5αRI) to 47.9 %. Logistic regression analysis showed a bidirectional relation between the occurrence of depressive symptoms and erectile dysfunction. The occurrence of both depressive symptoms and erectile dysfunction was related to severity of LUTS, nocturia, the use of 5αRI, comorbidity, and sedentary life style.ConclusionsPrevalence of depressive symptoms in patients diagnosed with BPH is associated with severity of LUTS, erectile dysfunction, nocturia, BPH pharmacotherapy (5αRIs), sedentary life style, and comorbidities including obesity.

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Section: Discussionmentioning

confidence: 99%

Depressive symptoms in patients diagnosed with benign prostatic hyperplasia

Pietrzyk

Olszanecka-Glinianowicz

Owczarek

et al. 2015

Int Urol Nephrol

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“…Another of this study's major findings is also found in the literature: a greater severity of current suicidal ideation and more previous suicide attempts are more common in patients with hazardous drinking habits. A previous epidemiological study suggested that, in patients with concurrent depressive and alcohol use disorders, depression exerted a stronger effect on suicide-related cognition and behaviors ( 37 ). A study of a community-based sample in Korea observed a significant association among unplanned suicidal attempt(s), alcohol use disorder, and major depressive disorder ( 38 ).…”

Section: Discussionmentioning

confidence: 99%

Hazardous Drinking-Related Characteristics of Depressive Disorders in Korea: The CRESCEND Study

Park

Lee

et al. 2015

J Korean Med Sci

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This study aimed to identify clinical correlates of hazardous drinking in a large cohort of Korean patients with depression. We recruited a total of 402 depressed patients aged > 18 yr from the Clinical Research Center for Depression (CRESCEND) study in Korea. Patients' drinking habits were assessed using the Korean Alcohol Use Disorder Identification Test (AUDIT-K). Psychometric scales, including the HAMD, HAMA, BPRS, CGI-S, SSI-Beck, SOFAS, and WHOQOL-BREF, were used to assess depression, anxiety, overall psychiatric symptoms, global severity, suicidal ideation, social functioning, and quality of life, respectively. We compared demographic and clinical features and psychometric scores between patients with and without hazardous drinking behavior after adjusting for the effects of age and sex. We then performed binary logistic regression analysis to identify independent correlates of hazardous drinking in the study population. Our results revealed that hazardous drinking was associated with current smoking status, history of attempted suicide, greater psychomotor retardation, suicidal ideation, weight loss, and lower hypochondriasis than non-hazardous drinking. The regression model also demonstrated that more frequent smoking, higher levels of suicidal ideation, and lower levels of hypochondriasis were independently correlates for hazardous drinking in depressed patients. In conclusion, depressed patients who are hazardous drinkers experience severer symptoms and a greater burden of illness than non-hazardous drinkers. In Korea, screening depressed patients for signs of hazardous drinking could help identify subjects who may benefit from comprehensive therapeutic approaches.Graphical Abstract

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“…Como indica a literatura científica, jovens do sexo feminino, baixo nível socioeconômico, com histórico de problemas de saúde, histórico familiar de transtorno mental, uso de drogas e presença de transtorno de humor apresentaram maior proporção de risco de suicídio (Adinkrah, 2011;Coêlho, Guarniero & Wang, 2010;Kirkcaldy, Siefen, Urkin & Merrick, 2006;Mulye & cols., 2009;Nordentoft & Pedersen, 2011;Shah, Veledar, Hong, Bremner, & Vaccarino, 2011;Turhan, Inandi, Aslan, & Zeren, 2011). Tais congruências sinalizam a necessidade de maior acurácia na identificação do risco de suicídio, em especial, no serviço de saúde pública, local de maior procura de indivíduos com comorbidades acima destacadas.…”

Section: Discussionunclassified

Risco de suicídio em jovens com transtornos de ansiedade: estudo de base populacional

et al. 2012

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ResumoEste estudo teve por objetivo verificar a relação entre a presença de transtornos de ansiedade e risco de suicídio em jovens. Em delineamento transversal de base populacional, os jovens respondiam a um questionário sobre questões sociodemográficas, comportamentais e de saúde. Avaliou-se o bem-estar psicológico através da Escala de Faces de Andrews e consumo de substâncias foi efetuado pelo Teste de Triagem do Envolvimento com Álcool, Cigarro e Outras Substâncias, (Alcohol, Smoking and Substance Involviment Screening Test -ASSIST). A Mini Internacional Neuropsychiatric Interview 5.0 avaliou transtornos de ansiedade e o risco de suicídio. Dos 1.621 jovens entrevistados, 20,9% apresentaram algum transtorno de ansiedade e 8,6% risco de suicídio. A presença de algum transtorno de ansiedade esteve significativamente associada ao risco de suicídio (RP 6,10 IC95% 3,95 a 9,43). Dessa forma, salienta-se a importância de maior atenção ao risco de suicídio também em pacientes com transtornos de ansiedade. Palavras-chave: Suicídio; Ansiedade; Distúrbios Mentais. Suicide risk in young adults with anxiety disorders: population-based study AbstractThis study aimed at investigating the relationship between the presence of anxiety disorders and suicide risk in young adults. In a cross-sectional population-based design young adults answered a questionnaire about sociodemographic, behavioral and health characteristics. The measure of psychological well-being was made by Faces Scale of Andrews while the substances use evaluation was performed according to the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST). The Mini International Neuropsychiatric Interview 5.0 evaluated anxiety disorders and suicide risk. Among the 1.621 young adults interviewed, 20.9% had some anxiety disorders and 8.6% suicide risk. After multivariate analysis, the presence of any anxiety disorder was significantly associated with suicide risk (PR 6.10 95% CI 3.95 to 9.43). Thus, it is highlighted the importance of greater attention to suicide risk in those patients with anxiety disorders.

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The influence of the comorbidity between depression and alcohol use disorder on suicidal behaviors in the São Paulo Epidemiologic Catchment Area Study, Brazil

Cited by 13 publications

References 39 publications

Depressive symptoms in patients diagnosed with benign prostatic hyperplasia

Depressive symptoms in patients diagnosed with benign prostatic hyperplasia

Hazardous Drinking-Related Characteristics of Depressive Disorders in Korea: The CRESCEND Study

Risco de suicídio em jovens com transtornos de ansiedade: estudo de base populacional

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