Food intake and serum levels of iron in children and adolescents with attention-deficit/hyperactivity disorder

Menegassi, Márcia; Mello, Elza Daniel de; Guimarães, Lísia Rejane; Matte, Bruno da Silva; Driemeier, Fernanda Munhoz; Pedroso, Fiona L.; Rohde, Luís Augusto; Schmitz, Marcelo

doi:10.1590/s1516-44462009005000008

Cited by 47 publications

(55 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, the results of the case control studies searching ferritin levels differ from each other. Donfrancesco et al [18], Menegassi et al [19] and Perçinel et al [17] did not find significant differences in ferritin levels between groups. On the contrary, some other studies detected lower ferritin levels in ADHD subjects [12,44,45].…”

Section: Discussionmentioning

confidence: 94%

“…According to parameters related to iron, CPRS total scores were not found associated with the Hb and ferritin levels in our study. Likewise, Donfrancesco et al [18], Millichap et al [43] and Menegassi et al [19] showed no significant relationship between ferritin levels and ADHD symptom scores in ADHD patients. However, Oner et al [14] found lower ferritin levels and higher CPRS, Conners' Teacher Rating Scale (CTRS) total scores in accordance.…”

Section: Discussionmentioning

confidence: 97%

“…Some studies have revealed that the severity of ADHD symptoms was related with low serum ferritin levels [12][13][14][15][16][17]. However, some other studies challenged these results and claimed that brain iron should be investigated in this kind of studies instead of serum ferritin levels [18,19].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Vitamin B12 and haemoglobin levels may be related with ADHD symptoms: a study in Turkish children with ADHD

Unal

Çelebi

Bildik

et al. 2018

Psychiatry and Clinical Psychopharmacology

View full text Add to dashboard Cite

OBJECTIVE: In this study, we evaluated vitamin B12 and iron parameters in Turkish children with ADHD in order to examine the relationship between ADHD symptoms and these parameters. METHODS: Drug-naive 100 ADHD patients, aged between 6 and 12 years old, were included in the study. None of them had acute or chronic diseases. All patients were assessed by using the Schedule for Affective Disorders and Schizophrenia for School Age Children -Present and Lifetime Version (K-SADS-PL). Conners Parent Rating Scale (CPRS) was used for screening ADHD symptoms and symptom severity. Blood samples were evaluated for ferritin, haemoglobin, MCV, RDW, and vitamin B12 parameters. RESULTS: We indicated an inverse relationship between haemoglobin levels and learning, anxiety subscale scores of CPRS. Also, vitamin B12 and psychosomatic subscale scores were found negatively related whereas the relationship was in the opposite direction for ferritin. Vitamin B12 level was negatively correlated with learning problems and psychosomatic subscales of CTRS in the combined subtype of ADHD. CONCLUSION: Vitamin B12 and iron support may be useful in treatment of childhood ADHD, especially for learning problems, besides medication. ARTICLE HISTORY

show abstract

Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 97%

See 1 more Smart Citation

Vitamin B12 and haemoglobin levels may be related with ADHD symptoms: a study in Turkish children with ADHD

Unal

Çelebi

Bildik

et al. 2018

Psychiatry and Clinical Psychopharmacology

View full text Add to dashboard Cite

show abstract

“…The results of recent studies regarding iron deficiency and ADHD have not been consistent. While some studies have reported a significant relationship between ADHD and low serum ferritin levels [16][17][18][19][20][21][22][23], others studies have reported no such relationship [15,[24][25][26][27]. Further, not all of these studies have compared the results of ADHD patients with those of healthy controls.…”

Section: Introductionmentioning

confidence: 99%

“…In this regard, it is important to enroll patients who are not using psychotropic medications in these studies. However, only seven of the present studies on the subject involve the stimulant-naive cases [15,25,27,[34][35][36][37].…”

Section: Introductionmentioning

confidence: 99%

Iron Deficiency Parameters in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder

Percinel¹,

Yazıcı

Üstündağ

2015

Child Psychiatry Hum Dev

View full text Add to dashboard Cite

The aim of this study is to compare iron deficiency parameters in patients with stimulant-naive attention-deficit/hyperactivity disorder (ADHD) and healthy controls, to investigate whether there are differences among the ADHD presentations, and to evaluate the relationship between ADHD symptom severity and serum ferritin levels. In addition, ADHD-Predominantly Inattentive (ADHD-PI) patients with restrictive hyperactivity/impulsivity symptoms were evaluated as a separate group with "restrictive inattention presentation" (ADHD-Rest) and were compared with other groups. Patients with ADHD-Rest are typically defined as having six or more symptoms of inattention and fewer than three symptoms of hyperactivity/impulsivity. A total of 200 ADHD cases consisting of 100 ADHD-Combine (ADHD-C) and 100 ADHD-PI and a total of 100 healthy control cases were included in the study. The Schedule for Affective Disorders and Schizophrenia for School Age Children-Present and Lifetime Version was performed in a semi-structured interview during the diagnosis. The Turgay DSM-IV-Based Child and Adolescent Behavior Disorders Screening and Rating Scale, the Conners' Rating Scale-Revised: Long Form (Parent-Teacher) (CPRSR:L, CTRS-R:L) were used for clinical evaluation. Hemogram, serum iron, iron binding capacity and serum ferritin levels were assessed. There were no significant differences between the ADHD patients and the healthy control cases in terms of iron deficiency parameters. Further, there were no significant differences among the ADHD presentations in terms of the same parameters, nor were there any significant differences when the groups were examined after the identification of the ADHD-Rest. The CPRS-R:L Hyperactivity and the CTRS-R:L Hyperactivity scores were negatively correlated with serum ferritin level in the ADHD group. To our knowledge, our current study is the first to compare serum ferritin levels in ADHD-Rest with other presentations of ADHD, and included the largest number of patients that were classified by ADHD presentations. Elucidation of these findings is important for both the etiology and treatment of ADHD.

show abstract

Environmental Risk Factors for Attention-Deficit/Hyperactivity Disorder

Kadlaskar,

Piergies,

Miller

2023

Clinical Handbook of ADHD Assessment and Treatment Across the Lifespan

View full text Add to dashboard Cite

Food intake and serum levels of iron in children and adolescents with attention-deficit/hyperactivity disorder

Cited by 47 publications

References 23 publications

Vitamin B12 and haemoglobin levels may be related with ADHD symptoms: a study in Turkish children with ADHD

Vitamin B12 and haemoglobin levels may be related with ADHD symptoms: a study in Turkish children with ADHD

Iron Deficiency Parameters in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder

Environmental Risk Factors for Attention-Deficit/Hyperactivity Disorder

Contact Info

Product

Resources

About