A b s t r a c t Objective: To review the neurobiological substrates of impulse control disorders. Pathological gambling is a main focus of the review in that most biological studies of the formal impulse control disorders have examined this disorder. Method: The medical database Medline from 1966 to present was searched to identify relevant articles that were subsequently reviewed to generate this manuscript. Results: Preclinical studies suggest that differential brain monoamine neuromodulation is associated …
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