Excessive daytime sleepiness in patients with depressive disorder

Chellappa, Sarah Laxhmi; Araújo, John Fontenele

doi:10.1590/s1516-44462006000200010

Cited by 73 publications

(41 citation statements)

References 14 publications

(6 reference statements)

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“…Recently, we observed a significant association (r = 0.80) between EDS and suicidal ideation in depressed patients [24]. This unequivocal result was striking, considering that no specific relation of EDS with suicidal ideation had been previously described.…”

Section: Eds and Depressionmentioning

confidence: 62%

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Chronobiology, excessive daytime sleepiness and depression: Is there a link?

2009

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The complaint of excessive daytime sleepiness (EDS), commonly encountered in clinical practice, may arise from a variety of psychiatric disorders, most importantly depression. Even though EDS frequently leads depressed patients to seek medical assistance, it is commonly under-evaluated and under-diagnosed. Therefore, a comprehensive understanding and management of EDS is essential in the clinical assessment of depression. Within a theoretical framework, a chronobiological approach may shed new light on the complex interaction of EDS and depression. In this review, studies on EDS and depression are summarized and discussed within the context of circadian and sleep regulatory mechanisms. Furthermore, potential chronobiological therapeutic strategies are proposed to address some of the unmet needs in the treatment of EDS and depression.

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Section: Eds and Depressionmentioning

confidence: 62%

“…In atypical depression, hypersomnia is frequent, with increased night sleep duration up to 12 h, combined or not with EDS [24]. Since both REM sleep and sleep duration are under strong circadian control, these sleep alterations may reflect disturbances in the circadian system of depressed patients.…”

Section: Depression and Circadian Rhythmsmentioning

confidence: 99%

Chronobiology, excessive daytime sleepiness and depression: Is there a link?

2009

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“…Excessive somnolence is a heterogeneous category, which covers specific pathological states as well as situationally determined conditions. Therefore, the heterogeneous nature of excessive somnolence may account for its relatively low association with suicidal ideation (Lichstein et al, 1994;Chellappa and Araújo, 2006). Differences regarding specific traits of suicidal ideation, such as, active and passive suicidal ideation, specific plans for suicide, and previous suicide attempts in patients with sleep disorders and depression, however, have not been fully explored (Mann et al, 1999).…”

Section: Discussionmentioning

confidence: 99%

Sleep disorders and suicidal ideation in patients with depressive disorder

Chellappa¹,

Araújo²

2007

Psychiatry Research

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An intrinsic association between suicidal ideation and sleep disorders in patients with depressive disorder has been observed in recent studies. This study was conducted in order to examine the relationship between suicidal ideation and sleep disorders, such as insomnia and excessive sleepiness, in outpatients with major depressive disorder. Seventy patients with diagnoses of major depressive disorder were interviewed and assessed with the Sleep Habits Questionnaire and the Beck Scale for Suicidal Ideation (SSI). Data analyses were performed through descriptive analysis, Students t-test, Chi-square test and logistic regression model, with a statistical significance of 5%. In this study, depressed patients had high SSI scores (6.12 ± 2.67), particularly for active suicidal ideation (1.61 ± 0.39) and specific plans for suicide components (1.51 ± 0.40). Depressed patients with insomnia had significantly higher SSI scores (7.39 ± 2.84), in relation to patients with excessive sleepiness (3.68 ± 1.73). Furthermore it was observed that insomniac patients had significantly higher scores on the following components: active suicide ideation, specific plans for suicide and previous suicide attempts. The results of multivariate analysis showed that only insomnia had a significant association with suicidal ideation. Thus, sleep disturbances, particularly insomnia, should be considered in the assessment of suicidal risk in outpatients with depressive disorder.

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“…Extra weight loss may be beneficial for improving mechanical loading on joints hypersomnolence, obstructive sleep apnea, depression [87,88], and for cosmetic reasons. However, managing obesity, T2D, and metabolic syndrome requires prioritization of resources and combined, "cause-driven" approaches [32,33].…”

Section: Overall Management Of Obesity and T2dmentioning

confidence: 99%

Preventing Long-Term Complications of Obesity, Type 2 Diabetes, and Metabolic Syndrome

Wimalawansa¹

2015

Endocrinol Metab Syndr

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During the past three decades, obesity and type 2 diabetes have become major public health problems worldwide. Together, these two are the most costly non-communicable diseases affecting most countries. Compared to the escalating management costs associated with their complications, the day-to-day management cost of these two diseases are relatively small. In addition to better management of these to diseases, the key is to not only to prevent people becoming obese and developing type 2 diabetes, but also to prevent associated complications. While implementing mass-scale public education on healthy diet and physical activities (sustainable positive lifestyle changes) on one side, patient-oriented, individualized, cause-driven, preventative approaches are essential for reducing the morbidities and mortalities associated with these two common diseases. Blindly following the standardized care of one-treatment-fits-all model is not only ineffective but also cost more in the long run, comparison to the intensive, individualize care model in preventing long-term complications and reducing management costs.

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Excessive daytime sleepiness in patients with depressive disorder

Cited by 73 publications

References 14 publications

Chronobiology, excessive daytime sleepiness and depression: Is there a link?

Chronobiology, excessive daytime sleepiness and depression: Is there a link?

Sleep disorders and suicidal ideation in patients with depressive disorder

Preventing Long-Term Complications of Obesity, Type 2 Diabetes, and Metabolic Syndrome

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