Transtorno do pânico e gravidez

Clinical management of perinatal anxiety disorders: A systematic review

“…Panic disorder Gentile (2008) Escitalopram (40 mg/day) and alprazolam (1.5 mg/day) Decrease in panic symptoms; healthy infant. Nascimento et al (2004) Nortryptiline (75 mg/day and 100 mg/day, respectively)…”

“…Furthermore, adding mirtazapine to the SSRIs treatment, the patient reported a dramatic decrease in nausea, insomnia and appetite loss without any neonatal complication in the baby (Uguz, 2013). With regard to tricyclic antidepressants (TCAs), PD patients treated with nortryptiline (Nascimento et al, 2004) and imipramine (Uguz et al, 2014;Ware and DeVane, 1990) benefited from pharmacotherapy, reporting remission of panic symptoms. In the largest clinical sample to date, based on the Clinical Global Impression-Improvement Scale (CGI-I), 75% of pregnant women responded to low doses of imipramine (10-40 mg/day) with a statistically significant reduction of the mean number of panic attacks per week from 12.9 to 2.7 before and after the treatment, respectively (Uguz et al, 2014) (Table 2).…”