Transtorno obsessivo-compulsivo: possíveis subtipos

Hounie, Ana Gabriela; Brotto, Sergio de A; Diniz, Juliana Belo; Chacon, Priscila; Miguel, Eurí­pedes Constantino

doi:10.1590/s1516-44462001000600005

Cited by 17 publications

(14 citation statements)

References 21 publications

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“…9 Besides substance use disorders, men were more likely to present attention deficit, hyperactivity, social phobia, affective, and anxiety disorders in general. 24,25,48 Some gender-related comorbidity findings in OCD, such as substance use and social phobia among men, and eating and impulse control disorders among women, seem to reflect a general trend of clinical samples with other mental disorders, as well as community samples. Therefore, it is noteworthy that major depression usually does not predominate among women with OCD, possibly indicating that depressive symptoms are intrinsically linked to OCS regardless of gender.…”

Section: Phenotypical Studiesmentioning

confidence: 99%

Gender differences in obsessive-compulsive disorder: a literature review

Mathis

Alvarenga

Funaro

et al. 2011

Rev. Bras. Psiquiatr.

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151

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Introduction: Obsessive-compulsive disorder (OCD) is a heterogeneous condition, in which subtypes have been proposed. Previous studies suggested that gender plays a relevant role in OCD phenotypic expression. This study aimed to review the literature on gender differences in clinical, genetic or familial aspects of OCD. Method: A conventional review was conducted, including all papers that investigated demographic, clinical, and genetic aspects of OCD according to gender. The search was based on data available in Medline and PsycINFO databases in the last 20 years, using as keywords: obsessive-compulsive disorder; and: gender, sex, male, female, demographic characteristics, clinical features, clinical characteristics, genetic, genes, genetics gender OCD, genes OCD, genes OCD males, genes OCD females. Results: Sixty three of 487 phenotypical and genetics studies were selected. Most studies indicate that male patients are more likely than females to be single, present early onset of symptoms and chronic course of the disorder, greater social impairment, more sexual-religious and aggressive symptoms, and greater comorbidity with tic and substance use disorders. Female patients present more contamination/cleaning symptoms and greater comorbidity with eating and impulse-control disorders. Genetic and family studies are inconclusive, but suggest that gender may play a role in the disease expression. Conclusions: Gender is a relevant factor that should be taken into account when evaluating OCD patients. More studies are necessary to determine whether in fact it defines a homogeneous and particular group in OCD. ©2011 Elsevier Editora Ltda. All rights reserved. Gender differences in obsessive- DesCRIPToRs:Obsessive-compulsive disorder; Gender identity; Sex; Phenotype; Genetics. ReVIeW ARTICLe 391Gender differences in obsessive-compulsive disorder: a literature review Diferenças de gênero no transtorno obsessivo-compulsivo: uma revisão da literatura ResumoIntrodução: O transtorno obsessivo-compulsivo (TOC) é um quadro heterogêneo, no qual subtipos têm sido propostos. Estudos anteriores sugerem que gênero desempenha papel relevante na expressão fenotípica. O objetivo foi realizar uma revisão convencional da literatura sobre diferenças de gênero em relação a aspectos clínicos e genéticos ou familiares do TOC. Método: Realizou-se uma revisão convencional da literatura incluindo todos os artigos que investigaram aspectos sociodemográficos, clínicos e genéticos do TOC, de acordo com o gênero. A pesquisa foi baseada em publicações disponíveis nas bases de dados Medline e PsycInfo nos últimos 20 anos, usando como palavras-chave: obsessive-compulsive disorder (OCD), e: gender, sex, male, female, demographic characteristics, clinical features, clinical characteristics, genetic, genes, genetics gender OCD, genes OCD, genes OCD males, genes OCD females. Resultado: Sessenta e três artigos de fenótipo e genética foram selecionados. Na maioria dos estudos, o sexo masculino associou-se mais que o feminino com: ser solteiro, ap...

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Section: Phenotypical Studiesmentioning

confidence: 99%

Gender differences in obsessive-compulsive disorder: a literature review

Mathis

Alvarenga

Funaro

et al. 2011

Rev. Bras. Psiquiatr.

Self Cite

151

View full text Add to dashboard Cite

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“…According to some studies, 14 26 however, found no correlation between the degree of insight and response to sertraline in a multicenter study.…”

Section: Early Onsetmentioning

confidence: 94%

Treating refractory obsessive-compulsive disorder: what to do when conventional treatment fails?

Franz

Paim

Araújo

et al. 2013

Trends Psychiatry Psychother.

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Tratando o transtorno obsessivo-compulsivo refratário: o que fazer quando tratamentos convencionais falham? Treating refractory obsessive-compulsive disorder:what to do when conventional treatment fails? AbstractObsessive-compulsive disorder (OCD) is a chronic and impairing condition. A very small percentage of patients become asymptomatic after treatment. The purpose of this paper was to review the alternative therapies available for OCD when conventional treatment fails. Data were extracted from controlled clinical studies (evidence-based medicine) published on the MEDLINE and Science Citation Index/Web of Science databases between 1975 and 2012. Findings are discussed and suggest that clinicians dealing with refractory OCD patients should: 1) review intrinsic phenomenological aspects of OCD, which could lead to different interpretations and treatment choices; 2) review extrinsic phenomenological aspects of OCD, especially family accommodation, which may be a risk factor for non-response; 3) consider non-conventional pharmacological approaches; 4) consider non--conventional psychotherapeutic approaches; and 5) consider neurobiological approaches.

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“…Embora a participação dos núcleos da base na fisiopatologia da distonia seja postulada, o envolvimento de outras regiões encefálicas, especialmente os córtices motor e sensitivo, vem sendo cada vez mais valorizado (Hallett, 1995(Hallett, , 2002Rona et al, 1998). Por sua vez, a classificação do TOC em possíveis subtipos poderia ganhar evidência adicional com relevantes implicações terapêuticas (Hounie et al, 2001).…”

Section: Revisão De Literaturaunclassified

Distonia primária e transtorno obsessivo-compulsivo

Dias

Hounie

Corrêa³

et al. 2007

J. bras. psiquiatr.

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Palavras-chavesDistonia primária, transtorno obsessivocompulsivo, núcleos da base. RESUMOObjetivo: Uma maior freqüência de transtorno obsessivo-compulsivo (TOC) em pacientes com distonia primária vem sendo relatada na literatura. O objetivo deste trabalho é revisar os estudos que investigaram a associação entre TOC e distonia primária. Métodos: Artigos que correlacionaram ambas as condições, incluindo estudos caso-controle, descritivos, relatos e série de casos, foram selecionados. As bases de dados avaliadas foram Medline e Lilacs. Resultados: Foram encontrados 12 artigos, sendo 8 estudos caso-controle e 4 séries ou relatos de casos. Metade dos estudos caso-controle observou mais sintomas obsessivo-compulsivos nos pacientes com distonia em relação a controles, enquanto a outra metade não. Conclusão: Os resultados são conflitantes, não sendo possível estabelecer uma conclusão definitiva acerca da associação entre distonia e TOC. ABSTRACT Objective: Patients with primary dystonia have been reported to have a major incidence of obsessive-compulsive disorder (OCD). The objective of the present work is to review the studies that

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Transtorno obsessivo-compulsivo: possíveis subtipos

Cited by 17 publications

References 21 publications

Gender differences in obsessive-compulsive disorder: a literature review

Gender differences in obsessive-compulsive disorder: a literature review

Treating refractory obsessive-compulsive disorder: what to do when conventional treatment fails?

Distonia primária e transtorno obsessivo-compulsivo

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