The present study was conducted at Maryout research station located at 35 kilometers southwestern Alexandria, Desert Research Center of Egypt. The study was carried out during the period from February to August 2014. Twenty adult Barki rams with average body weight 42.8 kg ± 0.46 were used in a complete randomized design with five groups (4 animals in each). The five groups were named according to the diet they were daily given: BH group: given berseem hay and used as a control group, MS group: given moringa stalks without treatment, MSF group: given moringa stalks treated with fungus (Trichodermareesei), MSY group: given moringa stalks treated with yeast; (Saccharomyces cervisiae) and MSB group: Given moringa stalks treated with bacteria (Cellulomonascellulasea). All groups were offered concentrate feed mixture (CFM) and roughages (60:40%) to cover their maintenance and productive requirements according to Kearl (1982). The CFM is composed of 28% cottonseed meal, 10% yellow corn, 44% wheat bran, 3% rice bran, 2% molasses, 3% limestone and 1% common salt production of Al-Marg manufacture. This CFM contained 14.95% crude protein and 65.64% TDN. Each type of the experimental roughages was offered to ad libitum. Water was offered to the animals twice daily through the duration of the experiment. Microbiological preparations: Microbiological preparations were undertaken in the laboratory of microbiology, Desert Research Center, Al-Matarya, Cairo, Egypt. Three different cultures medium were prepared, and used to inoculate a sterilized broth medium. The microbial strains were the bacteria Cellulomonascellulasea (c.cellulasea), the fungus Trichodermareesei (T.reesei) and the yeast culture Saccharomycescervisiae (S. cervisiae).The microorganisms were maintained on CzabekDox agar medium for T. reesei (Oxoid, 1982), yeast extract malt agar (YMA) medium for S.cervisiae (Pridham et al., 1958) and carboxymethyl cellulose (CMC) agar medium for C. cellulasea (Someya, 1980) at 30˚C until used. The inoculated mediums (cultures) were incubated at 30 ºC for 7 days for fungus and 3 days for yeast or bacteria. Large-scale application of each strain culture to chopped moringa stalks were prepared by adding 36 liters of one of the previous growth culture to 360 liters of tap water and mixed with 300 kg chopped moringa stalks. All roughages were mixed well, and then bagged, pressed in clean plastic bags holding 50kg, sealed, and kept in chamber for 21 days at room temperature. At the end of incubation period, lasted for 21 days, the treated materials were solar dried to stop activity of fungi and moisture content reached less than 10%, then packed and stored until used in feeding trials. The samples of feed were analyses for proximate analysis according to AOAC (1995). Cell wall constituents (NDF, ADF and ADL) were determined according to Van-Soest et al. (1991). Cellulose and hemicelluloses were calculated by difference. Histological preparations: Skin samples were taken from the mid side region which is considered as a standard follic...