Short versus standard duration antibiotic therapy for acute streptococcal pharyngitis in children

Abstract

The standard duration of treatment for acute group A beta hemolytic streptococcus (GABHS) pharyngitis with oral penicillin is 10 days.

Non‐surgical periodontal treatment in conjunction with 3 or 7 days systemic administration of amoxicillin and metronidazole in severe chronic periodontitis patients. A placebo‐controlled randomized clinical study

“…For example, in two recent reviews on short‐term AB administration in acute streptococcal pharyngitis in children (Altamimi et al. , ), it was concluded that a 3‐day oral AB regimen yielded comparable clinical and microbiological efficacy to that of standard treatment of 10 days. Furthermore, the short duration treatment had shorter periods of clinical symptoms (fever, throat soreness) and a lower risk of early clinical treatment failure.…”

Guideline for the management of acute sore throat

“…A Cochrane review and meta‐analysis [103] summarized the evidence regarding the efficacy of short‐duration newer antibiotics (2–6 days) compared with 10 days of oral penicillin in treating children with acute group A β‐haemolytic streptococcal pharyngitis. Twenty studies were included with 13 102 cases of acute group A β‐haemolytic streptococcal pharyngitis.…”

“…Altamimi [103] To summarize the evidence regarding the effect of 2-6 days of oral antibiotics in treating children with acute streptococcal pharyngitis, compared with a 10-day course of oral penicillin, on duration of symptoms, eradication of the organism, and recurrence and complication rates…”

Tonsillectomy and Adenoidectomy and Myringotomy With Tube Insertion

“…A full course of antibiotic therapy initiated within 9 days of the emergence of symptoms of streptococcal pharyngitis prevents development of rheumatic fever but has no effect on the risk for poststreptococcal glomerulonephritis. (5) Other microorganisms occasionally are implicated in pharyngitis. Immunocompromised patients or patients ear-nose-throat tonsillectomy/adenoidectomy already receiving antimicrobial therapy are at higher risk for candidal pharyngitis, which generally presents with painful white plaques scattered throughout the oral cavity and pharynx that bleed with manipulation.…”