Primary mucinous adenocarcinoma of the bladder with signet-ring cells: case report

Abstract

CONTEXT: Primary adenocarcinomas of the bladder are uncommon and usually occur by contiguity with or hematogenic dissemination of other adenocarcinomas such as colorectal, prostate and gynecological tract carcinomas. Mucinous and signet-ring cell histological patterns are even rarer and it is often difficult to morphologically distinguish them from metastatic colorectal adenocarcinoma. CASE REPORT: We present and discuss a rare case of primary mucinous adenocarcinoma of the bladder with signet-ring cells in a 57-year-old male patient. Other primary sites for the tumor had been excluded and, in the absence of digestive tract tumor and for confirmation that it was a primary bladder tumor, an immunohistochemistry study was performed.

Delayed post gastrectomy haematuria: A rare distant site of signet ring cell carcinoma metastasis

“…Primary signet ring cell carcinoma of the urinary bladder has been reported in more than 70 patients in literature, whereas the presence of secondary signet ring cell carcinoma is rare. 5 The most common secondary urinary bladder carcinoma spread direct from surrounding organs namely colorectal cancer (33%), prostate cancer (12%) and cervical cancer (11%).…”

A Case Report of Primary Mucinous Adenocarcinoma of Urinary Bladder with Review of Literature

“…By definition, these mucinous foci should constitute at least half of the tumour mass. In some cases, there is an admixture of extracellular and intracellular mucin; the latter resulting in signet ring configuration [9].…”

Primary Urachal Mucinous Adenocarcinoma of the Urinary Bladder

“…Mucinous adenocarcinoma of the urinary bladder includes extracellular mucin mixed with tumor cells. In some cases there is mixture of extracellular and intracellular mucin resulting in signet-ring configuration [5].…”