2004
DOI: 10.1590/s1516-31802004000500006
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Treatment of bone pain secondary to metastases using samarium-153-EDTMP

Abstract: Treatment with 153Sm-EDTMP can control the pain secondary to bone metastases effectively in most patients with breast and prostate cancer without significant side effects.

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Cited by 21 publications
(10 citation statements)
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“…153 Sm-ethylene diamine tetramethylene phosphonate, 223 Ra-dichloride therapy ( 223 Ra), and other bone-seeking agents; however, only 223 Ra has demonstrated improved survival (1)(2)(3)(4)(5)(6).…”
mentioning
confidence: 99%
“…153 Sm-ethylene diamine tetramethylene phosphonate, 223 Ra-dichloride therapy ( 223 Ra), and other bone-seeking agents; however, only 223 Ra has demonstrated improved survival (1)(2)(3)(4)(5)(6).…”
mentioning
confidence: 99%
“…However, only 223 Ra dichloride therapy ( 223 Ra) has demonstrated improved overall survival (OS). [6][7][8][9][10][11] With the increasing use of 223 Ra for the treatment of prostate cancer, we sought to investigate the association of various clinical and imaging factors that may relate to bone marrow depletion in patients undergoing this therapy.…”
mentioning
confidence: 99%
“…Sm-153 ve Tc-99m MDP'nin tüm vücut tutulumu ve lezyon / normal kemik oranları, bir dereceye kadar benzer olduğundan tedavi için hasta seçiminde ve takibinde Tc-99m MDP ile tüm vücut kemik sintigrafisi kullanılır. [27,28] Bu çalışmamızda literatür bilgileri ile uyumlu olarak bazal Tc-99m MDP tüm vücut kemik sintigrafisi görüntülerindeki metastatik odakların, Sm-153 EDTMP uygulaması sonrası elde edilen görüntülerdeki odaklar ile uyumlu olduğu görüldü. Tedavi uygulaması sonrası trombosit sayılarında geçici olarak azalma izlendi, ancak tıbbi müdahale gerektirecek herhangi bir komplikasyonla karşılaşılmadı.…”
Section: Discussionunclassified