Conventional chemotherapy for acute myeloid leukemia: a Brazilian experience

Abstract

These results are similar to those reported in the literature. However, relapse and mortality rates remain high, and a search for more aggressive strategies in order to prevent relapse is recommended.

Acute leukemias in Piauí: comparison with features observed in other regions of Brazil

“…Only 9 patients (4 children and 5 adults) had a low body mass index. The FAB subtypes of the patients are shown in Table 2 compared to those found in the study from Campinas (15). A similar distribution of FAB subtypes was found in children and adults in Teresina (P = 0.20).…”

“…The data on AML were compared with a monoinstitutional study of patients from Campinas, SP, southeast region (15), treated according to the TAD9 Protocol (using ara-C, daunorubicin, 6-thioguanin) from the German AML Study Group.…”

A ação do decanoato de nandrolona (Deca-durabolin®) sobre parâmetros hematológicos e proteína total plasmática de ratos (Rattus rattus) com depressão medular induzida após administração de sulfato de vincristina (Oncovin®)

“…Os índices hematimétricos VCM e CHCM não mostraram alteração (normocitose e normocromia), que era esperado para anemias causadas por depressão medular (PARCHMENT et al, 1998;PAGNANO et al, 2000;VITURI, 2000). Os valores de plaquetas também apresentaram leve queda, e a proteína total mostrou valores sem diferença estatisticamente significante.…”

“…No tratamento das neoplasias humanas e dos animais domésticos, a quimioterapia tem sido a conduta de escolha, mesmo estando amplamente documentado que esses medicamentos podem provocar efeitos colaterais indesejáveis, como depressão medular (PARCHMENT et al,1998;PAGNANO et al, 2000) . Dentre os quimioterápicos, a Ciência Rural, v.35, n.3, mai-jun, 2005. vincristina (Oncovin ® ) tem sido uma das drogas mais utilizadas pelos clínicos veterinários.…”

Characterization and analysis of the outcome of adults with acute myeloid leukemia treated in a Brazilian University hospital over three decades

“…However, while randomized clinical trials have reported high long-term survival rates, the results of population-based studies have shown long-term remissions in a quarter of patients only (4)(5)(6)(7). Furthermore, retrospective studies performed in developing countries have reported even lower overall survival rates (8)(9)(10)(11)(12)(13).…”