Papillary carcinoma in a thyroglossal duct: case report

Martins, Alessandro F.; Melo, Giulianno Molina de; Tincani, Álfio José; Lage, Henriette T.; Matos, Patrícia Francisca de

doi:10.1590/s1516-31801999000600005

Cited by 16 publications

(14 citation statements)

References 5 publications

(13 reference statements)

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“…They are very rare with a reported incidence of 0.7% to 1% of all thyroglossal cysts [1]. Carcinoma usually arises from the ectopic thyroid tissues within the thyroglossal cyst.…”

Section: Discussionmentioning

confidence: 99%

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A Rare Case of Carcinoma in the Thyroglossal Duct Cyst of an Elderly Patient

Sundaramurthi¹,

Vijayakumar²,

Dharanya³

et al. 2017

Cureus

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Thyroglossal duct cysts are the most common congenital abnormalities of the neck, constituting about 70% of all cervical neck masses in children and 7% of the adult population. The occurrence of carcinoma in a thyroglossal duct cyst is very rare (less than 1%). Malignancy of the thyroglossal duct cyst usually presents in the third or fourth decade of life. We report a case of carcinoma in the thyroglossal duct cyst, which presented for the first time in our elderly patient. A 76-year-old male presented with a 6 x 5 cm swelling in the anterior aspect of the neck. The swelling had been present for three months and had a variegated consistency. It moved with deglutition as well as with protrusion of the tongue. Intra-operatively, the lesion was cystic and was adherent to the hyoid bone. Sistrunk operation was done. The post-operative histopathology showed papillary carcinoma in the thyroglossal duct cyst. The standard treatment is Sistrunk procedure with close follow-up of the patient. Patients with metastatic disease require a total thyroidectomy and in the presence of neck secondaries, neck dissection has to be done.The diagnosis can be missed because of the rarity of this condition. Carcinoma should be suspected in a thyroglossal duct cyst when presenting for the first time in the elderly age group.

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“…They are very rare with a reported incidence of 0.7% to 1% of all thyroglossal cysts [1]. Carcinoma usually arises from the ectopic thyroid tissues within the thyroglossal cyst.…”

Section: Discussionmentioning

confidence: 99%

“…Malignancies of thyroglossal duct cysts are very rare and constitute about 0.7% to 1% of all the thyroglossal cyst cases. They usually present in the third decade of life, commonly in women, with a male: female ratio of 1:1.5 [1]. Papillary carcinoma is the most common histological type and carries a good prognosis.…”

Section: Introductionmentioning

confidence: 99%

A Rare Case of Carcinoma in the Thyroglossal Duct Cyst of an Elderly Patient

Sundaramurthi¹,

Vijayakumar²,

Dharanya³

et al. 2017

Cureus

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“…[6] The aetiology of squamous cell carcinoma, thyroid is uncertain as the thyroid gland lacks squamous epithelium. Three theories have been postulated in the development of squamous cell carcinoma.…”

Section: Discussionmentioning

confidence: 99%

Squamous Cell Carcinoma of Thyroglossal Duct Cyst

Bhojwani¹,

Kini²,

Karthik³

et al. 2016

jemds

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BACKGROUNDIncomplete atrophy of thyroglossal tract or retained epithelial cysts, creates the basis for the origin of a thyroglossal duct cyst. Thyroglossal duct cysts are the most common anomaly in thyroid development that occurs in 7% of adult population. In general duct cysts are benign and the incidence of a carcinoma in a thyroglossal duct cyst is very rare, the incidence of which is 1% of a ll cysts. The vast majority of these are papillary carcinoma (82%), other types of malignancies occurring being mixed papillary and follicular carcinoma, squamous cell carcinoma, follicular carcinoma and anaplastic carcinoma in descending order of frequency. Review of literature has revealed 25 reported cases of squamous cell carcinoma of the thyroglossal duct cyst till date. [1]

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“…Among the vairous types of neoplasia in TDC, a papillary thyroglossal duct cyst carcinoma has the best favorable prognosis, with occurrence of metastatic lesions in fewer than 2% of cases, while a squamous cell carcinoma has the worst prognosis [12]. …”

Section: Discussionmentioning

confidence: 99%

Invasive thyroglossal duct cyst papillary carcinoma: a case report

et al. 2009

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IntroductionA thyroglossal duct cyst is the most common congenital anomaly of the thyroid gland and midline masses in childhood (70% abnormality in childhood, 7% in adult). Carcinomas arising from a thyroglossal duct cyst are rare (only 1% of thyroglossal duct cyst cases) and characterized by relatively non-aggressive behavior and rare lymphatic spread. They are also diagnosed mostly during the third and fourth decades of life. About 85% to 92% of all thyroglossal duct cyst carcinomas are papillary carcinomas.Case presentationWe present the case of a 44-year-old Iranian woman with Cacausian ethnicity with a painless anterior neck mass that appeared gradually over three months. She had a history of frequent painful swelling of the anterior part of her neck, which subsided with antibiotic therapy. Thyroid functional tests were normal and a thyroid scinitigraphy showed a cold nodule in the left lobe of her thyroid. A computed tomography scan revealed a large, heterogeneous enhancing soft tissue mass with cystic components in the midline of the anterior neck space. This extended from the base of the tongue,(completely separated from its muscles, to the inferior aspect of the thyroid gland and showed the destruction of the hyoid bone and the thyroid cartilage. The diagnosis of a thyroglossal duct cyst with malignant transformation was maintained. A fine needle aspiration revealed papillary carcinoma.ConclusionThis patient's case is presented because of its rare, aggressive, and invasive nature and rare and unusual manifestation, as well as its rapid increase in size, the destruction of the hyoid bone, chondrolysis of the thyroid cartilage, lymph adenopathy and the existence of a cold nodule in the thyroid gland.

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Papillary carcinoma in a thyroglossal duct: case report

Cited by 16 publications

References 5 publications

A Rare Case of Carcinoma in the Thyroglossal Duct Cyst of an Elderly Patient

A Rare Case of Carcinoma in the Thyroglossal Duct Cyst of an Elderly Patient

Squamous Cell Carcinoma of Thyroglossal Duct Cyst

Invasive thyroglossal duct cyst papillary carcinoma: a case report

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