Effect of polyvinyl alcohol content and after synthesis neutralization on structure, mechanical properties and cytotoxicity of sol-gel derived hybrid foams

Abstract

Bioactive glass/polymer hybrids are promising materials for biomedical applications because they combine the bioactivity of these glasses with the flexibility of polymers. In this work it was evaluated the effect of increasing the PVA content of the on structural characteristics and mechanical properties of hybrid. The hybrids were prepared with 70 wt. (%) SiO 2 -30 wt. (%) CaO and PVA fractions of 20 to 60 wt. (%) by the sol-gel method. The structural and mechanical characterization was done by FTIR, SEM and compression tests. To reduce the acidic character of the hybrids due to the catalysts added, different neutralization solutions were tested. The calcium acetate alcoholic solution was the best neutralizing method, resulting in foams with final pH of about 7.0 and small sample contraction. The foams presented porosity of 60-85 wt. (%) and pore diameters of 100-500 µm with interconnected structure. An increase of PVA fraction in the hybrids improved their mechanical properties. The scaffolds produced provided a good environment for the adhesion and proliferation of osteoblasts.

Ultra-thin polytetrafluoroethene/Nafion/silica composite membrane with high performance for vanadium redox flow battery

“…5. In comparison with P/N and commercial Nafion 212, there is an additional absorption peaks around 806 cm -1 in the FTIR of P/N/S-7, which can be ascribed to the SieOeSi symmetric stretching vibration [23,24]. The absorption peaks at 1204 cm À1 and 1148 cm À1 are corresponding to the two bands which are anti-symmetric n as mode of CF 2 and SO 3 -groups in Nafion [25].…”

Comparison of the Effect of Sol-Gel and Coprecipitation Routes on the Properties and Behavior of Nanocomposite Chitosan-Bioactive Glass Membranes for Bone Tissue Engineering

“…Tests. The synthesis conditions of the hybrids typically resulted in a product of polymeric character that is sensitive to high temperatures, which prevents the elimination of toxic substances by thermal treatment [24]. When in contact with the culture medium, the dissolution of hybrid products may change the pH of the medium and the cell growth, promoting lower cell viability.…”

Characterization of Hybrid Bioactive Glass-polyvinyl Alcohol Scaffolds Containing a PTHrP-derived Pentapeptide as Implants for Tissue Engineering Applications

“…The development of inorganic-organic composites attempts to create a balance between strength and toughness, in turn improving the characteristics commonly found in the individual components of the composite. These composites can be synthesized through a hybridization route, combining two or more organic and inorganic components [ 10 - 15 ]. Sol-gel technology allows for the incorporation of different types of polymers within an inorganic silica bulk, thus producing organic-inorganic hybrid materials.…”