Background: Water sorption is one of the concern regarding acrylic resin denture base materials since itmight affect the dimensional stability of the prosthesis, furthermore the absorbed water may dramaticallycompromise the physical and mechanical properties. Methods: Three different commercial denture basematerials (heat-curing acrylic resin) available in local markets were used (Vertex, Ivoclarw and Luxacryl)to
evaluatewater sorption and the effect of dry andwet environment on the fracture toughness ofthese materi-als. Water sorption test was carried out according to international organization for standardization (ISO)
Specification 1567-2000.The fracture toughnesswasdeterminedusing single edge notch bending test(SEN-B) according to ISO 13586:2000. Results: Water sorption in term of percentage was highest for Ivoclar
(0.78%ofitsweight) andlowestforLuxacryl(0.68%ofitsweight). Statistical analysiswithtwo-wayAnalysis
of Variance (ANOVA)test showed a significant difference between different acrylic material groups, and be-tweendifferentwater immersiontimes (p<0.0001). For fracture toughness,ithas been foundthatthe Ivoclar
samples displayed the highest fracture toughness after 28 days of immersion in distilled water at room tem-perature.Statisticalanalysiswithtwo-wayANOVAtest showedasignificantdifference for fracturetoughness
between different acrylic material groups (P<0.04).Conclusion: in general, fracture toughness of denture base materials was highly-changed after immersionin water.