Physiological traits of the symbiotic bacterium Teredinibacter turnerae isolated from the mangrove shipworm Neoteredo reynei

Trindade-Silva, Amaro E.; Machado-Ferreira, Erik; Senra, Marcus Vinicius Xavier; Vizzoni, Vinicius Figueiredo; Yparraguirre, Luciana A; Leoncini, Orilio; Soares, Carlos A. G.

doi:10.1590/s1415-47572009005000061

Cited by 23 publications

(21 citation statements)

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“…(TURNER, 1966) and oceanographic conditions, mainly temperature and salinity (BORGES et al, 2014b;PATI et al, 2014). These conditions affect the survival (BARRETO et al, 2000) and also the activity of endosymbiont bacteria (DISTEL et al, 2002;HORAK;MONTOYA, 2014;TRINDADE-SILVA et al, 2009), thus also affecting the rate and amount of wood consumption.…”

Section: Differences In the Distribution And Abundance Of Teredinidaementioning

confidence: 99%

Differences in the distribution and abundance of Teredinidae (Mollusca: Bivalvia) along the coast of Rio de Janeiro state, Brazil

Maldonado

Skinner

2016

Braz. j. oceanogr.

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Teredinidae are wood-boring mollusks found in marine and estuarine regions. Evaluation of the distribution and abundance of Teredinidae is a very important task, as the impact of the destruction of wood in man-made structures is still underestimated, mainly in tropical regions. It is also know that temperature and salinity are key factors affecting the abundance and activity of Teredinidae due to their effects on the physiological responses of Teredinidae. The aim of this study was to evaluate the distribution and abundance of Teredinidae along the Rio de Janeiro coast according to temperature range and pattern. Artificial pine collectors were used and remained immersed for three months in four regions at 14 sites. We recorded seven species of Teredinidae, identified according to their pallets. Ilha Grande Bay was the region with the highest density and species richness, and the region with the lowest was Guanabara Bay. One gradient of abundance related to temperature was found. The most abundant species were Lyrodus floridanus and Teredo furcifera. Besides temperature, wood availability among regions was another important factor. For the first time, we recorded the occurrence of Bankia destructa on the Rio de Janeiro coast, but this record does not indicate any species introduction or expanding distribution range.

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Section: Differences In the Distribution And Abundance Of Teredinidaementioning

confidence: 99%

Differences in the distribution and abundance of Teredinidae (Mollusca: Bivalvia) along the coast of Rio de Janeiro state, Brazil

Maldonado

Skinner

2016

Braz. j. oceanogr.

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“…Of bacteria with sequenced genomes, the gill symbionts Teredinibacter turnerae T7901 and related strains are among the richest sources of biosynthetic gene clusters (BGCs), comparable in content to famous producers of commercial importance such as Streptomyces spp. (12)(13)(14)(15). This implies that shipworms might be a good source of new compounds for drug discovery.…”

Section: Introductionmentioning

confidence: 99%

Secondary metabolism in the gill microbiota of shipworms (Teredinidae) as revealed by comparison of metagenomes and nearly complete symbiont genomes

Altamia

Lin

Trindade-Silva

et al. 2019

Preprint

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SignificanceShipworms play critical roles in recycling wood in the sea and in shaping mangrove habitats. Symbiotic bacteria supply the enzymes that they need for nutrition and wood degradation. Here, we show that the same nutritional symbionts also have an immense capacity to produce a multitude of diverse and likely novel bioactive secondary metabolites. The compounds likely support the ability of shipworms to degrade wood in marine environments and include a compound under investigation for its therapeutic potential. Because many of the symbionts can be cultivated, they provide a model for understanding how secondary metabolism impacts microbial symbiosis in animals. AbstractShipworms, assisted by intracellular γ-proteobacteria in their gills, are the principal degraders of wood in the sea. Shipworm symbionts have been cultivated in the laboratory. The genomes of these symbionts, in addition to being replete with lytic enzymes capable of degrading wood and/or enzymes of thioautotrophic metabolism, are among the bacterial genomes richest in secondary metabolite genes. These cultivated symbionts represent the dominant species in the gills in diverse shipworm species. We investigated how the isolate secondary metabolites might impact the host animals: which bacterial pathways are present, how widely distributed they are, and how they vary. Focusing on 14 wood-eating shipworm specimens, we found between one to three major bacterial species in each gill, with each species comprising a complex mixture of closely related strains. The mixture allows the shipworm host to access a much more

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“…The complete genome sequencing of this endosymbiont has revealed that ∼7% of its genome is devoted to proteins involved in the biosynthesis of secondary metabolites (Yang et al. 2009), including antibiotics, suggesting that this bacterium is highly involved in the synthesis of bioactive metabolites required for the host survival (Trindade-Silva et al. 2009; Han et al.…”

Section: Introductionmentioning

confidence: 99%

An Unbiased Genome-Wide View of the Mutation Rate and Spectrum of the Endosymbiotic Bacterium Teredinibacter turnerae

Senra

Sung

Ackerman

et al. 2018

Genome Biology and Evolution

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Mutations contribute to genetic variation in all living systems. Thus, precise estimates of mutation rates and spectra across a diversity of organisms are required for a full comprehension of evolution. Here, a mutation-accumulation (MA) assay was carried out on the endosymbiotic bacterium Teredinibacter turnerae. After ∼3,025 generations, base-pair substitutions (BPSs) and insertion–deletion (indel) events were characterized by whole-genome sequencing analysis of 47 independent MA lines, yielding a BPS rate of 1.14 × 10−9 per site per generation and indel rate of 1.55 × 10−10 events per site per generation, which are among the highest within free-living and facultative intracellular bacteria. As in other endosymbionts, a significant bias of BPSs toward A/T and an excess of deletion mutations over insertion mutations are observed for these MA lines. However, even with a deletion bias, the genome remains relatively large (∼5.2 Mb) for an endosymbiotic bacterium. The estimate of the effective population size (Ne) in T. turnerae is quite high and comparable to free-living bacteria (∼4.5 × 107), suggesting that the heavy bottlenecking associated with many endosymbiotic relationships is not prevalent during the life of this endosymbiont. The efficiency of selection scales with increasing Ne and such strong selection may have been operating against the deletion bias, preventing genome erosion. The observed mutation rate in this endosymbiont is of the same order of magnitude of those with similar Ne, consistent with the idea that population size is a primary determinant of mutation-rate evolution within endosymbionts, and that not all endosymbionts have low Ne.

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Physiological traits of the symbiotic bacterium Teredinibacter turnerae isolated from the mangrove shipworm Neoteredo reynei

Cited by 23 publications

References 50 publications

Differences in the distribution and abundance of Teredinidae (Mollusca: Bivalvia) along the coast of Rio de Janeiro state, Brazil

Differences in the distribution and abundance of Teredinidae (Mollusca: Bivalvia) along the coast of Rio de Janeiro state, Brazil

Secondary metabolism in the gill microbiota of shipworms (Teredinidae) as revealed by comparison of metagenomes and nearly complete symbiont genomes

An Unbiased Genome-Wide View of the Mutation Rate and Spectrum of the Endosymbiotic Bacterium Teredinibacter turnerae

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