GenFlow: generic flow for integration, management and analysis of molecular biology data

Abstract

A large number of DNA sequencing projects all over the world have yielded a fantastic amount of data, whose analysis is, currently, a big challenge for computational biology. The limiting step in this task is the integration of large volumes of data stored in highly heterogeneous repositories of genomic and cDNA sequences, as well as gene expression results. Solving this problem requires automated analytical tools to optimize operations and efficiently generate knowledge. This paper presents an generic flow model , called GenFlow, that can tackle this analytical task.

An Extensible, Scalable Architecture for Managing Bioinformatics Data and Analyses

“…This makes it difficult when trying to produce a common general schema that can be shared among different communities. Researchers have attempted to integrate heterogeneous data at the semantic as well as the data source levels [21,23,24]. Attempts have also been made to standardize the representation of biological data and workflows [25].…”

Geração de expressões algébricas para processos de negócio usando reduções de digrafos série-paralelo

“…Em [1] Paralelamente ao estudo e especificação de padrões, a pesquisa em workflows e processos de negócio também presenciou o surgimento de problemas envolvendo ambientes dinâmicos de negócio e aplicações em domínios não-tradicionais, como, por exemplo, Ciências Naturais e automatização de ambientes laboratoriais [41]. Weske também discute o problema, enfatizando a necessidade de ferramentas mais flexíveis ou com capacidade de adaptaçãoàs mudanças [42].…”