Abstract:Human T-cell leukemia virus type 1 (HTLV-1) infection is endemic in Japan and several countries in South America, Caribbean and Africa. Endocrine and metabolic disorders have been variably reported to be associated with human T-cell leukemia virus type 1 (HTLV-1) infection. Therefore, the aim of this article was to critically evaluate the current knowledge of the endocrine and metabolic disorders associated with HTLV-1 infection. The literature search used PubMed, Web of Science, and LILACS databases in the pa… Show more
“…5 Hypercalcaemia is a prominent finding in 70-80% of patients with ATLL. 8 The underlying mechanisms are related to direct or indirect osteoclast activation mainly due to PTH-related peptide and pro-inflammatory cytokines and chemokines. 7,9,10 In the setting of ATLL, systemic hypercalcaemia can lead to extensive calcification.…”
Adult T-cell leukaemia-lymphoma is a rare haematological malignancy, which can cause severe hypercalcaemia and metastatic calcification resulting in life-threatening arrhythmias.
“…5 Hypercalcaemia is a prominent finding in 70-80% of patients with ATLL. 8 The underlying mechanisms are related to direct or indirect osteoclast activation mainly due to PTH-related peptide and pro-inflammatory cytokines and chemokines. 7,9,10 In the setting of ATLL, systemic hypercalcaemia can lead to extensive calcification.…”
Adult T-cell leukaemia-lymphoma is a rare haematological malignancy, which can cause severe hypercalcaemia and metastatic calcification resulting in life-threatening arrhythmias.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.