Nasal carriage of methicillin-resistant Staphylococcus aureus in university students

Prates, Karina Aparecida; Torres, Ana; Garcia, Lourdes Botelho; Ogatta, Sueli Fumie Yamada; Cardoso, Celso Luíz; Tognim, Maria Cristina Bronharo

doi:10.1590/s1413-86702010000300021

Cited by 17 publications

(24 citation statements)

References 15 publications

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“…Our result, 9.04 % (n=14)of MRSA nasal carriage is higher than those documented in Netherland and Brazil afore mentioned [4,7]. Likewise, MRSA nasal carriage of Danish veterinary practitioners (means professionally exposed to animals) was 3.9% [13] which is similar to the MRSA carriage rate in the general population (healthy individuals and outside the healthcare environment) estimated to be less than 4 % [14][15].However, this recorded rate seems to be lower compared to those reported among veterinarians from international study (12.5%) [6], from UK veterinarians (12.3%) [5] and intriguingly among unexposed Malagasy population (14.8%) [9].…”

Section: Discussioncontrasting

confidence: 54%

“…An international study reported that 12.5% (34/272) of veterinarians from nine country carried MRSA in the nares or their throat [6]. In a study of Brazilian university students, the percentage nasal carriage of Staphylococcus aureuswas 40.8% with 5.8% of MRSA strains where all of them were susceptible to most of the antimicrobial agents tested [7].…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of methicillin-resistant <i>Staphylococcus aureus</i> nasal carriage in Malagasy veterinary students

Rasamiravaka¹,

Nirinarimanana²,

Rasamindrakotroka³

2016

Af J Clin Exp Micro

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Purpose:Populations that are frequently in contact with animals such as veterinary students have been demonstrated to be at risk of MRSA carriage.Thus, it is relevant to generate baseline data in MRSA nasal carriage and multidrug resistance among Malagasy veterinary students (Madagascar).Method:A cross-sectional study was carried out among veterinary students coming for laboratory training. After their wise consent, nasal swabs of the anterior nares were carried out; and S. aureuswas isolated by selective chromogenic culture. They were then assessed for antimicrobial susceptibility. Results: Nasal swabs of 155 Malagasy veterinary students (Sex-ratio M/F: 0.91), enabled to isolate 30 (19, 35%) S. aureusstrains, among which 14 (46, 66 %) were méthicillin-resistant (MRSA). Risk factors analysis revealed that history of hospitalization, recent antibiotic intake and frequent contact with animals and livestock workers/veterinarians increase the risk of MRSA nasal carriage. Among MRSA nasal isolates, a high rate of multidrug resistance and particularly an intriguing resistance to gentamycin (20%) and vancomycin (7.14%) were observed. Conclusion: These results suggest that MRSA is spreading in Malagasy community requiringa strategic policy againstmultidrug resistant strains. Key

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Section: Discussioncontrasting

confidence: 54%

Section: Introductionmentioning

confidence: 99%

Evaluation of methicillin-resistant <i>Staphylococcus aureus</i> nasal carriage in Malagasy veterinary students

Rasamiravaka¹,

Nirinarimanana²,

Rasamindrakotroka³

2016

Af J Clin Exp Micro

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“…In agreement with our results, S. aureus was isolated from nasal swabs of 102 (40.8%) of the 250 volunteers, 2.4% of them were CA-MRSA carriers in Brazil. 26 In Palestine in 2011, the nasal carriage of MRSA among the students was 2.5%. 7 In 2010, a total of 322 University students in Taiwan were screened and 2.2%, of them harboured MRSA.…”

Section: Discussionmentioning

confidence: 99%

Methicillin resistant Staphylococcus aureus nasal colonization among secondary school students at Duhok City-Iraq

Habeeb¹,

Hussein²,

Assafi³

et al. 2014

Jmid

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Objective: Methicillin-resistant Staphylococcus aureus (MRSA) widely distributed in hospitals around the world. There is strong relationship between disease development and S. aureus nasal carriage. The aim of this study was to evaluate the prevalence and epidemiology of nasal colonization with S. aureus and MRSA in the community of Duhok city, Iraq.Methods: 489 students aged 16 to18 years were included. Nasal swab samples were collected followed by antimicrobial susceptibility test. MRSA isolates were selected and investigated for the mecA gene. Also the prevalence of PantonValentine Leukocidin (PVL) gene was also studied.Results: A total of 90 (18.4%) out of 489 (18.4%) of the students were found to be colonized by S. aureus. Only 10 (2.04%) of the students were found to be MRSA carrier. All MRSA isolates were sensitive to Vancomycin. PLV gene was detected in one MRSA strain. Conclusion:This is the first study investigating S. aureus colonization in students in the Duhok city. Nasal carriage of S. aureus and MRSA is comparable with reports from elsewhere. Fortunately, all trains included in our study were sensitive to vancomycin. Further research is needed to examine the SCCmec elements and the evolution of MRSA over the time.

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“…Staphylococcus aureus can be found as a harmless colonizer of skin and mucosa, mainly the anterior nares, in 20%-60% of the population [1][2][3]. Colonization by this bacterium is one important predisposing factor for staphylococcal infections [1].…”

Section: Introductionmentioning

confidence: 99%

Molecular and phenotypic characteristics of methicillin-resistant Staphylococcus aureus isolated from hospitalized patients

Oliveira

Morey

Santos

et al. 2015

J Infect Dev Ctries

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Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is one of the leading causes of infections acquired in both community and hospital settings. In this study, MRSA isolated from different sources of hospitalized patients was characterized by molecular and phenotypic methods. Methodology: A total of 123 S. aureus isolates were characterized according to their genetic relatedness by repetitive element sequence based-PCR (REP-PCR), in vitro antimicrobial susceptibility profile, SCCmec typing and presence of seven virulence factor-encoding genes. Results: REP-PCR fingerprinting showed low relatedness between the isolates, and the predominance of one specific lineage or clonal group was not observed. All isolates were susceptible to teicoplanin and linezolide. All isolates were resistant to cefoxitin and penicillin, and the majority were also resistant to one or more other antimicrobials. Fifty isolates (41.7%) were intermediately resistant to vancomycin. Most isolates harbored SCCmec type II (53.7%), followed by type I (22.8%), type IV (8.1%) and type III (1.6%). All isolates harbored at least two virulence factor-encoding genes, and the prevalence was as follows: coa, 100%; icaA, 100%; hla, 13.0%; hlb, 91.1%, hld, 91.1%; lukS-PV and lukF-PV, 2.4%; and tst, 34.1%. A positive association with the presence of hla and SCCmec type II, and tst and SCCmec type I was observed. Conclusion: This study showed the high virulence potential of multidrug-resistant MRSA circulating in a teaching hospital. A high prevalence of MRSA showing intermediate vancomycin resistance was also observed, indicating the urgent need to improve strategies for controlling the use of antimicrobials for appropriate management of S. aureus infections.

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Nasal carriage of methicillin-resistant Staphylococcus aureus in university students

Cited by 17 publications

References 15 publications

Evaluation of methicillin-resistant <i>Staphylococcus aureus</i> nasal carriage in Malagasy veterinary students

Evaluation of methicillin-resistant <i>Staphylococcus aureus</i> nasal carriage in Malagasy veterinary students

Methicillin resistant Staphylococcus aureus nasal colonization among secondary school students at Duhok City-Iraq

Molecular and phenotypic characteristics of methicillin-resistant Staphylococcus aureus isolated from hospitalized patients

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