Primary nodular hepatic tuberculosis mimicking hepatic neoplasia in an immunocompetent host

Dias, Levindo Tadeu Ferreira Figueiredo; Rodrigues, Gisane Cavalcanti; Barbosa, Diogo Santos; Lacerda, Domício Carvalho; Ruas, Marcelo Freire

doi:10.1590/s1413-86702009000200016

Cited by 5 publications

(3 citation statements)

References 11 publications

(14 reference statements)

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“…Oliva et al reported 23 cases of LHTB; in 20 of the 23 patients, the LHTB lesions were preoperatively misdiagnosed as carcinoma of the liver or a liver abscess (14). Common symptoms of hepatic TB include fever, weight loss and abdominal pain, which are nonspecific (6,10,15,16). A common laboratory abnormality is an elevated ALP level (5,6,14,16,17).…”

Section: Discussionmentioning

confidence: 99%

Localized Hepatic Tuberculosis with Imaging Changes Caused by the Progression of Tuberculosis

et al. 2016

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Localized hepatic tuberculosis (LHTB) is difficult to diagnose preoperatively, and most cases of LHTB are diagnosed based on pathological findings. A relationship between imaging features and the pathological stage of hepatic tuberculosis (TB) has recently been reported, which could aid in the diagnosis of hepatic TB. We herein present a case study of a patient with LHTB diagnosed postoperatively who demonstrated imaging changes due to the progression of TB. An awareness of the presence of LHTB might have permitted a preoperative diagnosis. This is the first report of an LHTB patient who exhibited imaging changes during the course of the disease.

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Section: Discussionmentioning

confidence: 99%

Localized Hepatic Tuberculosis with Imaging Changes Caused by the Progression of Tuberculosis

et al. 2016

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“…Although TB is a common disease worldwide, ATB is an unusual manifestation of extrapulmonary TB [2]. ATB poses significant diagnostic and management challenge.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Forty-Nine Patients with Abdominal Tuberculosis

Kılıç¹

2016

Ann Clin Anal Med

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(14), intestinal (5), and solid organ tuberculosis (2). The most frequent symptoms were abdominal pain, abdominal distention and fatique. Ascites appeared to be the most frequent clinical finding. Ascites and enlarged abdominal lymph nodes were the most frequent findings on ultrasonography and tomography. Diagnosis of abdominal tuberculosis was mainly depended on histopathology of ascitic fluid and biopsies from peritoneum, abdominal lymph nodes or colonoscopic materials. Forty patients healed with standart 6-month therapy while extended treatment for 9-12 months was needed in 8 whom had discontinued drug therapy and had persistent symptoms and signs. One patient died within the treatment period due to disseminated infection. Discussion: The diagnosis of abdominal tuberculosis is often difficult due to diverse clinical presentations. The presence of ascites, personal/familial/contact history of tuberculosis, and coexisting active extraabdominal tuberculosis are the most significant marks in diagnosis. Diagnostic laparoscopy and tissue sampling seem to be the best diagnostic approach for abdominal tuberculosis.

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“…Tuberculosis (TB) infection is still common today and remains an important cause of morbidity and mortality [ 1 , 2 ]. Abdominal TB is one of the most prevalent forms of extrapulmonary manifestation [ 3 ]. Hepatic involvement is uncommon and is categorized into 5 types: miliary, abscess, nodule, biliary invasion and serosal invasion.…”

Section: Introductionmentioning

confidence: 99%

Liver Tuberculosis Presenting as an Uncommon Cause of Pyrexia of Unknown Origin: Positron Emission Tomography/Computed Tomography Identifies the Correct Site for Biopsy

Yu¹,

Sheng²

2014

Med Princ Pract

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Objective: To identify the correct site to biopsy in a case of pyrexia of unknown origin (PUO) caused by hepatic tuberculosis (TB). Clinical Presentation and Intervention: A 58-year-old man who developed hepatic TB presented with PUO. Ultrasonography (US) and computed tomography (CT) of the abdomen showed only calcifications in the liver, and positron emission tomography (PET)/CT showed diffuse increased metabolic activity in addition to focal areas of increased activity. A diagnosis of hepatic TB was confirmed by histological examination of liver tissues and interferon-γ release assays (IGRAs of T-SPOT/TB). The patient was treated with 4 anti-tubercular therapies (rifampicin, isoniazid, ethambutol and pyrazinamide). At the 3-month follow-up, the patient was disease free as confirmed by abdominal US. Conclusion: PET/CT was helpful in identifying a site to biopsy that led to the correct diagnosis.

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Primary nodular hepatic tuberculosis mimicking hepatic neoplasia in an immunocompetent host

Cited by 5 publications

References 11 publications

Localized Hepatic Tuberculosis with Imaging Changes Caused by the Progression of Tuberculosis

Localized Hepatic Tuberculosis with Imaging Changes Caused by the Progression of Tuberculosis

Evaluation of Forty-Nine Patients with Abdominal Tuberculosis

Liver Tuberculosis Presenting as an Uncommon Cause of Pyrexia of Unknown Origin: Positron Emission Tomography/Computed Tomography Identifies the Correct Site for Biopsy

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