Fraturas transtrocanterianas: uso de alendronato no pós-operatório

Abstract

Objective: To evaluate the results of the use of alendronate sodium in postoperative transtrochanteric femoral fractures. Method: Over a six-month period, 75 patients were treated at the Orthopedic Service for transtrochanteric femoral fractures, undergoing surgery with 135 degree DHS plate fixation. We selected 19 patients who were healthy, cooperative, previously unable to walk, classified as type III according to Tronzo, whose contralateral hips had not undergone any previous surgery, enabling the evaluation of bone mineral density (BMD) in the immediate postoperative period and after six months. The patients were divided into groups I and II, with and without the use of alendronate sodium in the immediate postoperative period, respectively. The minimum follow-up was six months. After four weeks, the patients were evaluated according to the Visual Analogue Scale for Pain (VAS) in order to verify the rate of bone resorption, bone mass and radiological consolidation of the fracture. Results: There was a statistical trend of earlier radiological consolidation and lower bone resorption in patients with the use of alendronate sodium in post-fracture with established osteoporosis. Conclusion: We concluded that radiologically, patients using alendronate sodium showed faster bone consolidation, with a lower rate of resorption.

One-year mortality of elderly patients with hip fracture surgically treated at a hospital in Southern Brazil

“…A higher incidence was observed in female patients (74.4%); this finding is consistent with the literature, which indicates a ratio of two to five women for every man. 1 , 3 , 4 , 5 , 9 , 13 , 15 , 16 , 17 , 18 , 19 , 20 , 21 The mean age of patients included in the study was 79.84 years, similar to that found in the literature. 1 , 3 , 17 , 21 , 22 …”

“…Most often, trauma is low-energy and is related to factors such as malnutrition, impaired activities of daily living, decreased visual acuity and reflexes, sarcopenia, and – particularly – bone fragility. 1 , 5 , 6 …”

The analysis of alendronate action in bone fracture healing in rats

“…However, it was not a paired study comparing patients with and without osteoporosis. 19 Regarding the effect of alendronate on bone healing in fractures in oophorectomized rats, the study by Cao et al (2002) reported that this drug does not prevent the onset of fracture healing and callus formation, however, continued use prevents the bone remodeling process for a long period. 7 Systematic review in humans carried out by Molvik and Khan (2015) reports that for distal radius fractures bisphosphonate use was associated with a significantly longer time to healing.…”

Reprodutibilidade Intra E Inter Observadores Da Classificação De Tronzo Nas Fraturas Transtrocanterianas De Fêmur

“…Outra realidade é a dificuldade em classificar e avaliar o tipo de fratura e o grau da gravidade por conta da não padronização dos critérios de avaliação e as classificações usadas tanto na literatura como na prática clínica. Na literatura pesquisada, houve predominância nas seguintes classificações das fraturas do fêmur de acordo com a região anatômica: Do grupo AO (aebeisgemeinschaft für osteosynthesefragen) para as fraturas diafisárias, classificação de Garden para colo de fêmur, Tronzo para as transtrocanterianas (CARDOSO et al, 2011).…”