Avaliação clínica, laboratorial e radiográfica de brasileiros com espondiloartropatias

Bomtempo, Carlos Alexandre de Souza; Lage, Ricardo da Cruz; Ferreira, Gilda Aparecida; Carvalho, Marcos Alberto de

doi:10.1590/s0482-50042006000400002

Cited by 9 publications

(7 citation statements)

References 40 publications

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“…1,[25][26][27][28][29][30][31][32][33] Most patients were male, and ankylosing spondylitis was the most frequently found form of SPA, followed by undifferentiated SPA and psoriatic arthritis. Recent studies show a reversal of this relationship, with a higher prevalence of undifferentiated SPA than ankylosing spondylitis.…”

Section: Discussionmentioning

confidence: 99%

Nefropatia por IgA em portadores de espondiloartrites acompanhados no Serviço de Reumatologia do Hospital das Clínicas da UFMG

Azevedo¹,

Ferreira²,

Carvalho³

2011

Rev. Bras. Reumatol.

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Objective: To determine the frequency of glomerulonephritis in patients with spondyloarthritis followed-up at a Brazilian Rheumatology Service, and to evaluate the clinical variables associated. Patients and methods: Patients were assessed for sociodemographic characteristics, type of spondyloarthritis, time since diagnosis and disease activity, non-steroidal anti-infl ammatory drug use, HLA-B27 positivity, creatinine and urea serum levels, major comorbidities, hematuria and proteinuria. Patients with hematuria were subsequently assessed for the presence of dysmorphic red blood cells in urine, and those with proteinuria underwent 24-hour urine protein measurement. Renal biopsy was performed in patients with glomerular hematuria and/or proteinuria over 3.5 g/24-hour. Results: Seventy-six patients were assessed. Microscopic hematuria was the most frequently found abnormality in urinalysis (44.7%), usually intermittent and in spot urine samples during patients' follow-up. In eight patients (10.5%), glomerular hematuria was suspected. Renal biopsy was performed in fi ve of them, showing IgA nephropathy in four (5.3%) and thin membrane disease in one patient. Conclusions: A high frequency of urinalysis alterations was observed in that subgroup of patients, as well as a high prevalence of IgA nephropathy. Although further studies on this subject are needed to better clarify these results, periodic urinalysis of patients with spondyloarthritis should be recommended.

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Section: Discussionmentioning

confidence: 99%

Nefropatia por IgA em portadores de espondiloartrites acompanhados no Serviço de Reumatologia do Hospital das Clínicas da UFMG

Azevedo¹,

Ferreira²,

Carvalho³

2011

Rev. Bras. Reumatol.

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“…Nevertheless, positive HLA-B27 was statistically associated with male gender, which agrees with other Brazilian studies. 12,13 We observed a significant inverse correlation between HLA values and Schober's test, which assesses the lumbar spine flexibility. …”

Section: Discussionmentioning

confidence: 72%

“…10 World wide the positivity of HLA-B27 may vary from 4%, as confirmed by Israeli researchers to 36.4% as observed in the Brazilian state of Minas Gerais. 11,12 …”

Section: Discussionmentioning

confidence: 99%

HLA-B27 frequency in a group of patients with psoriatic arthritis

Ruiz

Azevedo²,

Lupi

2012

An. Bras. Dermatol.

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BACKGROUNDHLA-B27 is associated with spondyloarthritis, a group of diseases that includes psoriatic arthritis. OBJECTIVESTo describe the HLA-B27 frequency in a group of Brazilian patients with psoriatic arthritis and correlate its presence or absence with their clinical manifestations. METHODSCross-sectional study with 44 psoriatic arthritis patients of a Rheumatology clinic. Demographic and social data were recorded, as were skin and joints clinical examination. HLA-B27 was tested. All data were processed descriptively and comparatively by appropriate software. Parametric and non parametric tests were used with 5% statistical significance. RESULTSHLA-B27 was negative in 32 of the 44 patients (72,7%). Most of them were male, Caucasian, living in Rio de Janeiro, with plaque type psoriasis and average age of 52,9 years. There was statistical significant correlation between positive HLA-B27 and male gender (p=0,004). Negative HLA-B27 had a tendency to correlate with hands and wrists arthritis (p=0,07). There was an inverse significant correlation between HLA values and Schöber's test (p=0,02). CONCLUSIONAlthough HLA-B27 is negative in most of patients, it is significantly associated to male gender and inversely correlated with Schöber's test.

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“…Mesmo com uma carência relevante de informações na literatura especializada, é possível considerarmos o gene HLA-B27 como um marcador de susceptibilidade para o desenvolvimento de espondilite anquilosante, sendo necessário ainda estabelecer o real contexto de correlação entre tais fatores (7) .…”

Section: Introductionunclassified

Espondilite Anquilosante na adolescência: um relato de caso

Marques¹,

Silva²,

Guimarães³

et al. 2022

CONJ

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Objetivo: apresentar um relato de caso de uma adolescente com espondilite anquilosante (EA) e sua evolução. Descrição do caso: adolescente, sexo feminino, 18 anos de idade, com quadros de lombalgia, cervicalgia intensa, artralgia em ombros, joelhos e dores abdominais, com confirmação diagnóstica de EA. Segue em tratamento terapêutico. Discussão: A EA cursa com um comprometimento no esqueleto axial, podendo evoluir com rigidez e limitação funcional progressiva do esqueleto axial, a paciente do caso, apresentou alterações nas articulações sacroilíacas, principalmente do lado direito. O protocolo terapêutico segue em andamento com o uso do adalimumabe, tendo em vista que não respondeu ao tratamento com antiiflamatórios não esteroidais e continua em acompanhamento fisioterápico.

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Avaliação clínica, laboratorial e radiográfica de brasileiros com espondiloartropatias

Cited by 9 publications

References 40 publications

Nefropatia por IgA em portadores de espondiloartrites acompanhados no Serviço de Reumatologia do Hospital das Clínicas da UFMG

Nefropatia por IgA em portadores de espondiloartrites acompanhados no Serviço de Reumatologia do Hospital das Clínicas da UFMG

HLA-B27 frequency in a group of patients with psoriatic arthritis

Espondilite Anquilosante na adolescência: um relato de caso

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