Graham-Little Piccardi Lassueur Syndrome: case report

Steglich, Raquel Bissacotti; Tonoli, Renata Elise; Pinto, Giselle Martins; Müller, Fernanda Melo; Guarenti, Isabelle Maffei; Duvelius, Ernani Siegmann

doi:10.1590/s0365-05962012000500019

Cited by 12 publications

(10 citation statements)

References 5 publications

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“…The histopathologic features of extrafacial keratotic papules of Graham–Little–Piccardi syndrome show the typical features of lichen planopilaris, with dilated keratin plugged follicular openings with apoptotic keratinocytes and lichenoid interface dermatitis and perifollicular concentrical fibrosis and perifolliculitis . In this sense, our report demonstrates that the extrafacial hyperkeratotic papules of FFA are histopathologically similar to those of Graham–Little–Piccardi syndrome.…”

Section: Discussionsupporting

confidence: 67%

Histopathology of keratotic papules of the limbs in frontal fibrosing alopecia

Fernández-Flores

Manjón

2016

J Cutan Pathol

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Frontal fibrosing alopecia (FFA) is a scarring type of alopecia that presents clinically as progressive frontotemporal hairline regression and eyebrow loss, mainly in postmenopausal women. An additional common finding is keratotic papules on the face or (less commonly) on the trunk and extremities. The histopathology of the facial keratotic papules associated with FFA is the same as that of lichen planopilaris. There are very few FFA cases with biopsies from extrafacial sites and no cases of folliculocentric keratotic papules with biopsies from extrafacial sites. In the current report, we describe the histopathology of one such keratotic papule from the arm of a 75-year-old woman with FFA and show that the morphology is that of lichen planopilaris and that the papules are identical to those found in Graham-Little-Piccardi syndrome.

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Section: Discussionsupporting

confidence: 67%

Histopathology of keratotic papules of the limbs in frontal fibrosing alopecia

Fernández-Flores

Manjón

2016

J Cutan Pathol

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“…Graham‐Little syndrome is an uncommon variant of LPP clinically characterized by cicatricial alopecia of the scalp, NCA of the axilla and pubis and follicular papules over trunk and extremities . Perifollicular hyperkeratosis and accentuation of follicular ostia were the scalp trichoscopic findings reported in only one case report with trichoscopy …”

Section: Resultsmentioning

confidence: 99%

“…2 Perifollicular hyperkeratosis and accentuation of follicular ostia were the scalp trichoscopic findings reported in only one case report with trichoscopy. 49…”

Section: Graham-little Syndromementioning

confidence: 99%

Trichoscopy of primary cicatricial alopecias: an updated review

Mathur

Acharya

2019

Acad Dermatol Venereol

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Trichoscopy is an emerging technique for the evaluation of various hair and scalp disorders including primary cicatricial alopecias (PCAs). Early diagnosis of PCAs can lead to effective management and trichoscopy could be a useful aid during this process. Multiple studies have reported the trichoscopic features of PCAs, however, a focused review evaluating these disorders with their trichoscopic features is lacking. With the objective of evaluating the trichoscopic findings reported in the literature for various PCAs, we conducted a systematic literature search in PubMed and Embase. The search yielded 310 studies in a total of which 54 studies were included in our review. Majority of these studies originated from the Caucasian or Asian population. Through this review, we provide an overview of the frequent and specific trichoscopic findings in different PCAs with their clinical significance where applicable based on the current knowledge and identify the areas for future research.

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“…The follicular hyperkeratotic plugs on dermoscopy correspond to the dilated follicular infundibula with hyper-keratosis on histology [7]. Dermoscopy of Grahm-Little-Piccardi syndrome shows follicular hyperkeratosis and accentuation of follicular ostia [8].…”

Section: Discussionmentioning

confidence: 97%

Fox-Fordyce Disease: Dermoscopic Perspective

Singal

Kaur

Jakhar

2020

Skin Appendage Disord

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Fox-Fordyce disease (FFD) is a rare chronic skin disease of the apocrine unit. It presents chiefly in postpubertal females as grouped, monomorphic, skin-colored follicular papules associated with intense pruritus commonly in axillae but may involve pubic, perineal, areolar, and umbilical areas [An Bras Dermatol. 2018;93(1):161–2]. Diagnosis is mostly clinical as histological features are often nonspecific and variable. However, the lesions at times may be mistaken for irritant contact dermatitis, lichen nitidus, syringoma, etc. [J Dermatol. 2009;36(9):485–90]. Dermoscopy is being increasingly utilized in pigmentary and inflammatory skin disorders. In this communication, we describe the dermoscopic features in FFD, which shows typical light brown to dark brown folliculocentric structureless areas with loss of dermatoglyphics. Some of the lesions also show hyperkeratotic follicular plugging.

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Graham-Little Piccardi Lassueur Syndrome: case report

Cited by 12 publications

References 5 publications

Histopathology of keratotic papules of the limbs in frontal fibrosing alopecia

Histopathology of keratotic papules of the limbs in frontal fibrosing alopecia

Trichoscopy of primary cicatricial alopecias: an updated review

Fox-Fordyce Disease: Dermoscopic Perspective

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