Periungual leishmaniasis

Periungual and paronychia-like skin lesions can mimic various diseases, setting up a diagnostic challenge that invariably requires correlation with complementary tests. We report a case of an ulcerated tumor of the nailfold diagnosed as leishmaniasis. Although paronychia-like cutaneous leishmaniasis is a rare variant, its epidemiological relevance in Brazil should prompt dermatologists to include it as a plausible diagnosis thus leading to correct work up and treatment.

Section: Discussionmentioning

confidence: 99%

Periungual tegumentary leishmaniasis: a diagnostic challenge

Sasso

Torino

França

et al. 2017

“…16 Although the ulcerated form comprises the vast majority of ATL cases, the disease can evolve with indeterminate clinical features. 17 …”

Section: Clinical Diagnosismentioning

confidence: 99%

Complementary exams in the diagnosis of american tegumentary leishmaniasis

Gomes

Paula

Morais

et al. 2014

Self Cite

The diagnosis of American Tegumentary Leishmaniasis is a difficult but essential task when considering the high toxicity profile of the drugs available. Since the discovery of its etiologic agent, numerous diagnostic tests have been developed. None of the tests available today can be considered as the gold standard, since they do not add enough accuracy for the disease detection. Good epidemiological and clinical knowledge of the disease are fundamental precepts of the dermatology practice and precede the rational use of existing diagnostic tests. In this article we aim, through extensive literature review, to recall fundamental concepts of any diagnostic test. Subsequently, based on this information, we will weave important comments about the characteristics of existing diagnostic tests, including immunological tests such as Montenegro's skin test, serology and detection of parasites by direct examination, culture or histopathology. Finally we will discuss the new technologies and options for the diagnosis of Cutaneous Leishmaniasis. The molecular biology technique is considered a promising tool, promoting the rapid identification of the species involved. We also aim to educate dermatologists about a disease with high morbidity and assist in its difficult recognition.

“…3,4,7 Using an association of pentoxifylline in the treatment regime was effective probably due to its immunomodulatory function and its ability to regulate tumor necrosis factor- α levels. 8-10 …”

Section: Reportmentioning

confidence: 99%

Recurrent cutaneous leishmaniasis

Gomes

Damasco

Morais

et al. 2013

Self Cite

We present a case of an 18-year-old male patient who, after two years of inappropriate treatment for cutaneous leishmaniasis, began to show nodules arising at the edges of the former healing scar. He was immune competent and denied any trauma. The diagnosis of recurrent cutaneous leishmaniasis was made following positive culture of aspirate samples. The patient was treated with N-methylglucamine associated with pentoxifylline for 30 days. Similar cases require special attention mainly because of the challenges imposed by treatment.