Vasculite de pequenos vasos como primeira manifestação clínica de paracoccidiodomicose: relato de caso

Abstract

Paracoccidioidomycosis is a systemic disease caused by inhalation of conidia of Paracoccidioides brasiliensis, a dimorphic fungus that initially affects the airway, spreading by lymphatic and hematogenous routes to various organs and systems, and that can be fatal if the diagnosis and treatment are not correct. The authors describe a patient who presents small vessel vasculitis as an initial manifestation of the disease, which is an atypical clinical form with a single description in the literature.

Fatal septic shock caused by Paracoccidioides brasiliensis phylogenetic species S1 in a young immunocompetent patient: a case report

“…Septic shock can cause peripheral hypoperfusion and hypoxia, inducing gangrene of the extremities. Another even stronger hypothesis for the digital gangrene in this case is that an intense inflammatory response damaged the endothelium, causing a severe vasculitis process 9 .…”