Micose fungoide: relato de caso tratado com radioterapia

Abstract

Mycosis fungoides is a rare type of non-Hodgkin's lymphoma of T cells that primarily affects the skin. It is characterized by the presence of erythematous plaques that evolve into ulcerated lesions, tumors throughout the skin or even bone marrow infiltration in advanced stages. Chemotherapy and topical steroids, phototherapy and radiotherapy are treatment options for early cases. This study reports the case of patient with multiple tumor lesions in the skin already biopsied with diagnosis of mycosis fungoides. The patient was refractory to both treatments with topical chemotherapy and phototherapy. It was then indicated total skin irradiation with electrons. Keywords: Lymphoma, T-Cell, cutaneous; Mycosis fungoides; Radiotherapy Resumo: Micose fungoide é um tipo de linfoma não Hodgkin de células T raro que acomete primariamente a pele. Caracteriza-se pela presença de placas eritematosas que evoluem para lesões ulceradas, tumores em toda a pele ou ainda infiltração de medula óssea em estágios avançados. Como opção de tratamento para os casos iniciais, tem-se quimioterapia e corticoterapia tópica, fototerapia e radioterapia. Este estudo relata o caso de um doente com múltiplas lesões tumorais na pele já biopsiadas com diagnóstico de micose fungoide. O paciente foi refratário ao tratamento com quimioterapia tópica e fototerapia, sendo então indicada irradiação total da pele com elétrons. Palavras-chave: Linfoma cutâneo de células T; Micose fungoide; Radioterapia

Case for diagnosis

“…1 Surgical excision was used in the past for few small lesions, but the excellent response to topical and/or radiation therapy rendered surgical intervention obsolete. 4,5 Localized PR has good prognosis without extracutaneous dissemination or disease-related deaths. 1 In contrast, the few published cases of KGD report fatal outcomes, systemic involvement and interferon therapy, with an 8-month followup without relapse.…”