Perfil nosológico de centro de referência em dermatologia no estado do Amazonas - Brasil

Raposo, Adriana Andrade; Schettini, Antônio Pedro Mendes; Sardinha, José Carlos; Pedrosa, Valderiza

doi:10.1590/s0365-05962011000300007

Cited by 7 publications

(9 citation statements)

References 17 publications

(29 reference statements)

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“…In Brazil, for example, 57,343 cases of skin diseases had been identified, with acne being the most frequently disorder observed [11]. Sexually transmitted diseases, allergic skin diseases, unspecified dermatoses, leprosy, seborrhea, and related diseases were also identified [12]. Based on these reports, it is evident the importance of the search for new and alternative therapeutic options for the care of different skin conditions.…”

Section: Introductionmentioning

confidence: 99%

Evidence of Bioactive Compounds from Vernonia polyanthes Leaves with Topical Anti-Inflammatory Potential

Rodrigues

Chibli

Santos

et al. 2016

IJMS

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Vernonia polyanthes Less. (Asteraceae), popularly known as “assa-peixe”, is a plant species used in Brazilian traditional medicine for the treatment of cutaneous damage, cicatrization, inflammation, and rheumatism. Based on these ethnopharmacological findings, the current study evaluated the topical anti-inflammatory effects of the hexane (HEVP) and ethyl acetate (EAEVP) extracts from V. polyanthes leaves in experimental models of skin inflammation. Chemical characterization was carried out by HPLC–UV/DAD analysis. Anti-inflammatory activity was evaluated using Croton oil-, arachidonic acid (AA)-, phenol-, ethyl phenylpropiolate (EPP)-, and capsaicin-induced ear edema models in mice. Histopathological evaluation and measurements of myeloperoxidase (MPO) and N-acetyl-β-d-glucosaminidase (NAG) enzymes were also performed. Rutin, luteolin, and apigenin were identified in EAEVP. Topically applied HEVP and EAEVP significantly (p < 0.05, p < 0.01 or p < 0.001) reduced edema induced by five different irritants at the doses tested (0.1, 0.5 and 1.0 mg/ear). Histopathological analysis revealed a reduction of edema, inflammatory cell infiltration, and vasodilation. In addition, the enzymes activity (MPO and NAG) in the ear tissues was reduced by the topical treatment of HEVP and EAEVP (p < 0.05, p < 0.01 or p < 0.001). The results suggest that V. polyanthes leaves are effective against cutaneous damage, which support its traditional use and open up new possibilities for the treatment of skin disorders.

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Section: Introductionmentioning

confidence: 99%

Evidence of Bioactive Compounds from Vernonia polyanthes Leaves with Topical Anti-Inflammatory Potential

Rodrigues

Chibli

Santos

et al. 2016

IJMS

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“…The psoriasis frequencies described by the studies in Table 1 are similar to data from the literature, which estimate that 1%–2% of the populations in Germany, Britain, and the USA are affected. 6 , 37 Previous data from a census provided by the Brazilian Society of Dermatology in 2005 estimated a 2.5% frequency based on a multicentric population from 17 states, including private and public dermatology services. 38 Higher frequencies were found among alcoholic individuals in comparison to nonalcoholic controls.…”

Section: Discussionmentioning

confidence: 99%

“… Notes: ( A ) Estimated prevalence of psoriasis in an Amazonian state (Northern Brazil); 37 ( B ) Psoriasis is the most frequent cause of erythroderma (44.9%) in São Paulo. 48 White skin color predominates in the southern states, while black and brown skin colors predominate in northeastern and northern Brazil.…”

Section: Figurementioning

confidence: 99%

Epidemiology and treatment of psoriasis: a Brazilian perspective

Duarte¹,

Porto-Silva²,

Oliveira³

2015

PTT

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Psoriasis is a chronic immune-mediated systemic disease that is influenced by genetic and environmental factors, is associated with comorbidities, and has a negative impact on the quality of life of affected individuals. The prevalence of psoriasis varies among different ethnic groups, but this topic has not been studied in Brazil to date. In this review, we evaluate the epidemiology and treatment of psoriasis from a Brazilian perspective. We focused on studies that involved Brazilian subjects. The prevalence of psoriasis in Brazil is estimated to be 2.5%, but no population study has been performed previously. Environmental factors, such as tropical climate, in association with genetic factors, such as miscegenation, may exert a beneficial impact on the course and frequency of psoriasis in Brazil. A number of studies have advanced our understanding of the cardiovascular, ophthalmic, and oral comorbidities that are associated with psoriasis. Concerns about biological therapy, such as endemic leprosy, human T-cell lymphotropic virus (HTLV), and tuberculosis infections, are discussed. The nonavailability of treatment options for psoriasis in the public health system contradicts the Brazilian Society of Dermatology guidelines, stimulating the judicialization of access to medicines in psoriasis care.

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“…Nesse contexto, as monitorias acadêmicas se mostram como ferramentas de ensino que contribuem para o aperfeiçoamento de práticas inerentes à formação e para o aprofundamento de conhecimentos relativos à área (ANDRADE et al,2018).…”

Section: Introductionunclassified

A Trajetória Da Cientificidade Da Enfermagem No Mundo: Relato De Experiência

Corrêa¹,

Caldas²,

Sobrinho³

et al. 2020

A Enfermagem Centrada Na Investigação Científica 4

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Perfil nosológico de centro de referência em dermatologia no estado do Amazonas - Brasil

Abstract: The pattern of skin diseases identified in this study may serve as a baseline to managers of health system in the region develop strategies for prevention and control of dermatoses, with emphasis on sexually transmitted diseases, allergic skin diseases, leprosy and acne.

Cited by 7 publications

References 17 publications

Evidence of Bioactive Compounds from Vernonia polyanthes Leaves with Topical Anti-Inflammatory Potential

Evidence of Bioactive Compounds from Vernonia polyanthes Leaves with Topical Anti-Inflammatory Potential

Epidemiology and treatment of psoriasis: a Brazilian perspective

A Trajetória Da Cientificidade Da Enfermagem No Mundo: Relato De Experiência

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