Infecções causadas por fungos demácios e suas correlações anátomo-clinicas

Hoffmann, Camila de Camargo; Danucalov, Itamara Pereira; Queiroz‐Telles, Flávio

doi:10.1590/s0365-05962011000100021

Cited by 13 publications

(6 citation statements)

References 9 publications

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“…The incidence of phaeohyphomycosis in transplanted patients is increasing in the last decades due to the increased number of transplanted patients and the use of imunosuppressants, the majority of cases occur two years after transplantat. Calcineurin inhibitors appear to further increase susceptibility to fungal infections when compared to other immunosuppressants [5,12].…”

Section: Discussionmentioning

confidence: 99%

Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report

Espanhol

Recuero

Pagani

et al. 2020

Medical Mycology Case Reports

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We report a case of phaeohyphomycosis that affected the leg of a 45-year-old Brazilian man, car mechanic and renal transplanted. The direct mycological examination evidenced dematiaceous septated hyphae. The pathogenic fungal species was identified as Exophiala xenobiotica. Antifungal activity in vitro revealed terbinafine as the best antifungal. For treatment, it was chosen surgical excision of the entire lesion and used systemic itraconazole. Phaeohyphomycosis caused by Exophiala xenobiotica is extremely rare and is closely related to transplant patients.

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Section: Discussionmentioning

confidence: 99%

Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report

Espanhol

Recuero

Pagani

et al. 2020

Medical Mycology Case Reports

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“…From 1980 to 2014, the main bacterial agents identified in Brazil were Nocardia brasiliensis [15,26,27–32], Nocardia asteroides [15,33], Nocardia caviae [34], Actinomadura madurae [13,35,36], Actinomadura pelletieri [14], and Streptomyces somaliensis [15]. For eumycetoma were Madurella mycetomatis [15,25,37,38], Madurella grisea [39–45], Acremonium falciforme [46], Acremonium kiliense [47], Scedosporium apiospermum [12,18,48,49,50], Fusarium solani [51], Exophiala jeanselmei [44,52,53] and Aspergillus sp. [12].…”

Section: Discussion and Review Of The Literaturementioning

confidence: 99%

Review of 21 cases of mycetoma from 1991 to 2014 in Rio de Janeiro, Brazil

et al. 2017

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Mycetoma is caused by the subcutaneous inoculation of filamentous fungi or aerobic filamentous bacteria that form grains in the tissue. The purpose of this study is to describe the epidemiologic, clinic, laboratory, and therapeutic characteristics of patients with mycetoma at the Oswaldo Cruz Foundation in Rio de Janeiro, Brazil, between 1991 and 2014. Twenty-one cases of mycetoma were included in the study. There was a predominance of male patients (1.3:1) and the average patient age was 46 years. The majority of the cases were from the Southeast region of Brazil and the feet were the most affected anatomical region (80.95%). Eumycetoma prevailed over actinomycetoma (61.9% and 38.1% respectively). Eumycetoma patients had positive cultures in 8 of 13 cases, with isolation of Scedosporium apiospermum species complex (n = 3), Madurella mycetomatis (n = 2) and Acremonium spp. (n = 1). Two cases presented sterile mycelium and five were negative. Six of 8 actinomycetoma cases had cultures that were identified as Nocardia spp. (n = 3), Nocardia brasiliensis (n = 2), and Nocardia asteroides (n = 1). Imaging tests were performed on all but one patients, and bone destruction was identified in 9 cases (42.68%). All eumycetoma cases were treated with itraconazole monotherapy or combined with fluconazole, terbinafine, or amphotericin B. Actinomycetoma cases were treated with sulfamethoxazole plus trimethoprim or combined with cycles of amikacin sulphate. Surgical procedures were performed in 9 (69.2%) eumycetoma and in 3 (37.5%) actinomycetoma cases, with one amputation case in each group. Clinical cure occurred in 11 cases (7 for eumycetoma and 4 for actinomycetoma), and recurrence was documented in 4 of 21 cases. No deaths were recorded during the study. Despite of the scarcity of mycetoma in our institution the cases presented reflect the wide clinical spectrum and difficulties to take care of this neglected disease.

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“…Rhinocladiella aquaspersa [17, 18] and Exophiala dermatitidis are less frequently reported. It has also been observed that Exophiala jeanselmei [19–21] and E. spinifera [22–25], normally responsible for the development of phaeohyphomycosis, produce muriform cells in typical lesions of CBM. In recent years other species that may be the agents of CBM have been described: Fonsecaea monophora [26, 27] , Fonsecaea nubica [28] and Phialophora richardsiae [29].…”

Section: Aetiological Agentsmentioning

confidence: 99%

Chromoblastomycosis

Krzyściak¹,

Pindycka-Piaszczyńska²,

Piaszczyński³

2014

pdia

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Chromoblastomycosis is a chronic fungal infection of the skin and subcutaneous tissue. The infection usually results from a traumatic injury and inoculation of microorganism from a specific group of dematiaceous fungi (usually Fonsecaea pedrosoi, Phialophora verrucosa, Cladophialophora carrionii). In the tissues fungi produce characteristic sclerotic cells or muriform cells. Dermal lesions can range from small nodules to large papillary-like eruptions. The disease has been described worldwide but the prevalence is higher in rural populations in countries with a tropical or subtropical climate, such as Madagascar in Africa and Brazil in South America. Diagnostic techniques are based on direct examination, culture and histopathology. Despite a variety of treatment modalities, which include long courses of antifungals, surgical excision and destructive physical therapies, the disease remains one of the most difficult deep mycotic infections to eradicate.

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Infecções causadas por fungos demácios e suas correlações anátomo-clinicas

Cited by 13 publications

References 9 publications

Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report

Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report

Review of 21 cases of mycetoma from 1991 to 2014 in Rio de Janeiro, Brazil

Chromoblastomycosis

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