Carcinoma epidermoide como complicação letal de lesões crônicas de cromoblastomicose

Abstract

A cromoblastomicose é uma micose subcutânea, ocasionada por fungos dermatófitos, dos gêneros: Fonsecaea, Phialophora e Cladophialophora. As complicações habituais são: infecções secundárias, linfedema e elefantíase. Em lesões crônicas, tem-se documentado malignização. Relatamos um caso de um homem de 72 anos de idade, com cromoblastomicose de 30 anos de evolução, em região glútea, com desenvolvimento de carcinoma epidermoide.

Chromoblastomycosis

“…Foot and shin swelling leads to elephantiasis. Carcinogenesis, which is an infrequent serious complication of chronic CBM, results in the development of squamous cell carcinoma [94–97]. …”

Squamous cell carcinoma arising from a chromomycosis lesion caused by Rhinocladiella aquaspersa with postsurgical recurrence of chromomycosis

“…The infection can spread contiguously, with rarely reported lymphatic and hematic dissemination. 7 Azevedo et al 3 found that 3 of 7 patients in his study experienced recurrence of chromomycosis after amputation; however, not many other studies support these findings. Possible causes for recurrence of chromomycosis are inadequate treatment, chronicity of the disease, and a deficient immune system.…”

A verrucous plaque on the lower leg

“…Chromoblastomycosis infection rarely has systemic complications and this is the reason why patients refer to their physician in late stages of the infection. Squamous cell carcinoma may rarely arise in chromoblastomycosis lesions [ 4 ]. A case of osseous infection due to overlying chromoblastomycosis has also been described [ 5 ].…”