Professor Sebastiao de Almeida Prado Sampaio

Rivitti, Evandro A.; Bagatin, Ediléia

doi:10.1590/s0365-05962009000300019

Cited by 8 publications

(20 citation statements)

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“…10 In this study, specific skin locations were not obtained, due to the great topographic variability of this pathology, thus opting to perform the location by segments: face, trunk, limb. 11 Melanoma skin tumors equally affect females and males, whereas non-melanomic skin tumors affect females more. 1 Males were more affected by cutaneous malignant tumors with 26 cases, while females with a total of 20 patients.…”

Section: Discussionmentioning

confidence: 99%

An epidemiological study of malignant skin tumors at Casa de Saúde hospital

SJ¹,

DT²,

LF³

2023

JCPCR

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Section: Discussionmentioning

confidence: 99%

An epidemiological study of malignant skin tumors at Casa de Saúde hospital

SJ¹,

DT²,

LF³

2023

JCPCR

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“…Além deste processo, a evolução para célula queratinizada envolve a decomposição do núcleo e demais organelas, bem como o espessamento da membrana plasmática. Neste processo há mudança do pH, que passa de aproximadamente neutro (pH 7,17) no estrato granuloso, para um pH ácido na superfície do estrato córneo (pH de 4,5 a 6,0) (RIVITTI, 2018;ROSS;PAWLINA, 2018).…”

Section: Ultraestrutura Dos Queratinócitosunclassified

Aspectos morfofisiopatológicos do melasma

Marinho

Feliciano²,

Nascimento³

et al. 2023

PRW

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Introdução: A pele é o órgão que delimita o organismo, e que possui como função a proteção contra danos causados pelos raios ultravioletas, realizada pela melanina, a qual é produzida nos melanócitos e transferida para os queratinócitos. O melasma é uma afecção de pele resultante de uma produção anormal deste pigmento, e que causa transtornos emocionais, psicossociais e diminuição da qualidade de vida. Objetivo: Explicar sobre os mecanismos de ativação do melasma, utilizando o estudo sobre as células envolvidas e a síntese de melanina para a construção do conhecimento. Fundamentação Teórica: A partir das pesquisas que pautaram as fontes para a construção deste estudo, observa-se a íntima relação que ocorre entre melanócitos e queratinócitos no que tange à fisiopatologia do melasma. Sabendo que o melasma é uma alteração estética de difícil tratamento, conhecer a morfologia celular e bioquímica envolvidas em seu mecanismo fisiopatológico é a maneira mais adequada de compreender as questões relacionadas ao sucesso ou ao fracasso de seu tratamento. Conclusão: Este estudo elucida sobre a morfofisiologia das células envolvidas no melasma e seus mecanismos de formação, sendo base de estudo para profissionais da área.

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“…It affects the pilosebaceous follicles through processes of hyperkeratinization, sebaceous hypersecretion, microbial colonization, such as by Cutibacterium acnes, formerly called Propionibacterium acnes, and immune mechanisms of inflammation Zaenglein et al (11). Such pathology can be divided into non-inflammatory when the comedones are not inflamed and inflammatory according to the predominant lesions, thus, it is classified from I to V according to the severity of the cases (12). Grade I acne is known to be non-inflammatory, also called comedonian.…”

Section: Pathophysiology Of Acnementioning

confidence: 99%

“…Finally, grade V is known to be the form of fulminant acne, since it is accompanied by an abrupt onset, with systemic manifestations, ranging from fever, leukocytosis and arthralgia. Therefore, this last degree is the most rare and severe form (12). The sequence of events most studied in the pathogenesis of acne corresponds to: a) obstruction of the hair follicle (in the infundibulum, the portion from the epidermis to the point where the sebaceous glands discharge), secondary to the abnormal desquamation of follicular keratinocytes; b) increase in sebum production; c) proliferation of anaerobic bacteria C. acnes and d) immune and inflammatory reactions triggered by C. acnes (13).…”

Section: Pathophysiology Of Acnementioning

confidence: 99%

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Ozonized oils: a review of its quality control, stability and effectiveness in the treatment of Acne vulgaris

Teixeira¹,

Ondina²,

Cruz³

et al. 2021

Drug Anal. Res.

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Acne affects most young people and its topical treatment with antibacterials is associated with increased bacterial resistance to antibiotics and adverse effects. As an alternative, ozone therapy stands out through the application of ozonized oils. The objective of this work was to raise the scientific evidence about the effectiveness in the treatment of acne, in addition to the techniques of characterization and stability of ozonated oils. This is an exploratory, descriptive study with a quantitative approach, based on the analysis of scientific references in a bibliographic review of the expository type, of the last 20 years. Among the selected references, only four manuscripts reporting clinical studies of ozone therapy, with controversial results. Seven articles with the physicochemical characterization of ozonated oils were found. The major part of manuscripts reported the use of sunflower, sesame and olive oil. The more common techniques used to characterize the ozonation process are the peroxide value (PV) and the iodine index (Ii), which represents the proportion of unsaturated groups, whose values increase and decrease, respectively with ozonization progress. The viscosity of oils is increased by the formation of polymeric peroxides; the FTIR spectrum, which identifies the decrease in the stretch bands C = C, in addition to ozone formation, monitored by NMR, are also employed. Increased antimicrobial activity has been demonstrated with the ozone level of the oils, but the activity against Cutibacterium acne has not been reported. Only two article reported satisfactory stability for 6 months of refrigerated ozonized oil or kept at room temperature, showing the need for more specific research to support the application of ozonized oils in the treatment of acne and stability data of these products.

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Professor Sebastiao de Almeida Prado Sampaio

Cited by 8 publications

References 0 publications

An epidemiological study of malignant skin tumors at Casa de Saúde hospital

An epidemiological study of malignant skin tumors at Casa de Saúde hospital

Aspectos morfofisiopatológicos do melasma

Ozonized oils: a review of its quality control, stability and effectiveness in the treatment of Acne vulgaris

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