Erupções vesicopustulosas benignas no neonato

Abstract

Neonatal vesicopustular eruption comprise a group of disorders with onset in the first four weeks of life. These conditions present multiple differential diagnoses and can be usually identified by clinical examination or simple laboratory procedures. Dermatologists should be able to recognize these eruptions, and most importantly, to differenciate them from serious and life-threatening dermatoses. Keywords: Acne; Candidiasis; Herpes simplex; Impetigo; Literature review; Melanosis; Newborns; Scabies

E se Não é o Que Parece?

“…5 O diagnóstico é clínico, contudo alguns exames podem auxiliar na confirmação da suspeita clínica, tais como a coloração de Giemsa ou Wright do conteúdo da lesão que revela neutrófilos e eventuais eosinófilos, e as culturas bacterianas e virais que são negativas. 6 O diagnóstico diferencial da MPTRN é extenso, sendo as doenças infecciosas o principal, tais como candidíase, varicela, infecções por herpes simplex ou bacterianas, sendo o seu rápido reconhecimento crucial. 4,5 No caso das infecções bacterianas a coloração Gram do conteúdo das pústulas mostra presença de microorganismos e a positividade na solução de hidróxido de potássio aponta para candidíase.…”

Dermatoses neutrofílicas: parte II

“…[97][98][99] The etiopathogenesis of the disease remains unknown. It is assumed that IAP represents a cyclic hypersensitivity skin reaction to antigenic components or antigens associated with prior infection with Sarcoptes scabiei.…”

“…97.105 Despite being an exclusively cutaneous and self-limited disease, it can cause sleep disturbances, irritability and poor appetite. 97,98,101 Cytological examination of the pustule shows a large amount of neutrophils and some eosinophils. 98 Histopathology is characterized by intraepidermal vesicles containing neutrophils and occasional eosinophils, focal degeneration of keratinocytes, and in some cases, dermal edema.…”

“…Negative potassium hydroxide smear and negative bacterial culture help to distinguish between congenital cutaneous candidiasis and staphylococcal pustulosis, respectively. 98,101,102 Dyshydrosis mainly affects adults and older children. Lesions predominate on the sides of fingers and subcorneal pustule is not seen on histopathology.…”

“…Lesions predominate on the sides of fingers and subcorneal pustule is not seen on histopathology. 98 Pustular psoriasis has a later onset and prolonged course. 101 Impetigo has larger pustules and bacterial culture identifies the causative agent 98 Scabies is a disease in which differentiation with IAP is more difficult because it is located on the palms and soles, is intensely pruriginous and rapidly becomes pustular.…”