Da hemoterapia dessensibilizante do passado à terapia imunomoduladora atual por imunoglobulina endovenosa em altas doses

Rivitti, Evandro A.

doi:10.1590/s0365-05962005000700012

Cited by 2 publications

(1 citation statement)

References 37 publications

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“…81 In dermatology, IVIG has been used in several autoimmune diseases, especially bullous diseases such as pemphigus vulgaris and bullous pemphigoid and also in collagen diseases such as vasculitis. 81,84 Its form of action is not fully understood. IVIG is generally well tolerated.…”

Section: (Vi) Therapies Of Still Poorly Understood Mechanismsmentioning

confidence: 99%

Vasculopatia livedoide: uma doença cutânea intrigante

Criado

Rivitti

Sotto

et al. 2011

An. Bras. Dermatol.

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Livedoid vasculopathy is a skin disease that occludes the blood vessels of the dermis. It has a pauciinflammatory or non-inflammatory nature. It is characterized by the presence of macular or papular, erythematous-purpuric lesions affecting the legs, especially the ankles and feet, and producing intensely painful ulcerations, which cause white atrophic scars called "atrophie blanche". This review includes studies and case reports found in the medical literature regarding the etiopathogenic associations of the disease, particularly those related to thrombophilia, their histopathological findings and the therapeutic approaches used in the difficult clinical management of these cases. Keywords: Leg ulcer; Livedo reticularis; Thrombophilia; Thrombosis; Venous thrombosis Resumo: A vasculopatia livedoide é uma afecção cutânea oclusiva dos vasos sanguíneos da derme, de caráter pauci-inflamatório ou não-inflamatório. Caracteriza-se pela presença de lesões maculosas ou papulosas, eritêmato-purpúricas, nas pernas, especialmente nos tornozelos e pés, as quais produzem ulcerações intensamente dolorosas, que originam cicatrizes atróficas esbranquiçadas, denominadas "atrofia branca". Nesta revisão, abordamos os estudos e relatos de caso da literatura médica referentes às associações etiopatogênicas da doença, particularmente as que se referem aos estados de trombofilia, seus achados histopatológicos e abordagens terapêuticas empregadas na difícil condução clínica destes casos.

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Section: (Vi) Therapies Of Still Poorly Understood Mechanismsmentioning

confidence: 99%

Vasculopatia livedoide: uma doença cutânea intrigante

Criado

Rivitti

Sotto

et al. 2011

An. Bras. Dermatol.

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The Effectiveness of Autohemotherapy in Chronic Urticaria Treatment in the Dr. Mohammad Hoesin General Hospital and Pertamina Hospital Palembang

Husan

Zulkarnain

Thaha

et al. 2020

BIKK

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Background: Chronic urticaria (CU) is one of the most common case found in dermatology and venereology and it decreases the quality of life. Autohemotherapy (AHT) is an innovative therapy that works by desensitization and activation of the local immune system, and it is effective for recurrent or refractory urticaria. AHT technique is simple, inexpensive, and does not require special expertise that can be done at all levels of health services in Indonesia. Purpose: to determine the effectiveness of AHT in the CU treatment. Methods: This was a clinical trial research with involving patients with CU in the Allergo-Immunology Clinic of Department of Dermatology and Venereology Dr. Mohammad Hoesin General Hospital (DV RSMH) and Pertamina Hospital Palembang. The Urticaria Activity Score (UAS7) and Dermatology Life Quality Index (DLQI) assessments were carried out on week 1 and week 10. Result: The research was conducted from 1 July - 30 September 2019 involving 72 eligible patients with 2 dropouts (2.8%). The mean age was 47 years (15-72 years), with 46 (63.9%) are women. Chronic spontaneous urticaria (CSU) was the most frequent diagnosis observed in 64 people (88.9%). Adverse events included bruises at the injection site (n=1; 1.4%) and at the blood draw location (n=1; 1.4%). On week 1, mean UAS7 was 30.77 ± 2.46, mean DLQI 21.66 ± 3.60. By week 10, UAS7 and DLQI significantly decrease to 4.12 ± 2.89 and 2.51 ± 1.53 (p <0.005). Conclusion: There was a significant decrease in UAS7 and DLQI in chronic urticaria patients after receiving AHT therapy for 10 weeks. This research concluded AHT can serve as an option in chronic urticaria treatment.

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Da hemoterapia dessensibilizante do passado à terapia imunomoduladora atual por imunoglobulina endovenosa em altas doses

Cited by 2 publications

References 37 publications

Vasculopatia livedoide: uma doença cutânea intrigante

Vasculopatia livedoide: uma doença cutânea intrigante

The Effectiveness of Autohemotherapy in Chronic Urticaria Treatment in the Dr. Mohammad Hoesin General Hospital and Pertamina Hospital Palembang

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