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Abstract

Syndrome in question CASE REPORTA 32-year-old female patient has presented skin lesions for five months. Upon examination, there were well-delimited achromic patches, which were symmetrically located in the temporal and eyebrow regions, dorsum of hands and shoulders. She had poliosis circumscribed to eyelashes, eyebrows and scalp (Figures 1 e 2).One month before the onset of skin lesions, she presented one episode of intense headache and fever, followed by dysacusia, conjunctival hyperemia and bilateral amaurosis. Therefore, she had to be admitted to hospital and bilateral uveitis was the confirmed diagnosis ( Figure 3). CSF analysis revealed meningitis with mononuclear (lymphocytic) infiltration and brain CT scan showed diffuse cerebral edema. At hospital she was given high doses of systemic steroids and recovered from neurological and ophthalmologic conditions after 20 days.

Síndrome de Vogt-Koyanagi-Harada e o seu acometimento multissistêmico

“…typical ocular findings are sunset glow fundus, Dalen-Fuchs nodules, and migration or accumulation of the pigmented epithelium of the retina 39 . Around two to three months after the onset of syndrome symptoms, it becomes possible to detect cutaneous findings such as vitiligo, alopecia and poliosis, which last is present in 80 to 90% of patients 10,42 . The recurrent phase does not affect all patients, but by definition just those who suffer with repeated outbreaks of ocular inflammation.…”