The antibacterial activity of propolis produced by Apis mellifera L. and Brazilian stingless bees

Fernandes, Ana Angélica Henrique; Leomil, Luciana; Sforcin, José Maurício

doi:10.1590/s0104-79302001000200003

Cited by 33 publications

(23 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In Brazil for instance, Africanized bees (Apis mellifera scutellata) are found in addition to native South American bees (e.g. Melipona and Tetragonisca species) (Sheppard et al, 1991;Fernandes Jr et al, 2001). The former bee type tends to gather bud exudates of the plant Baccharis dracunculifolia (Asteraceae), whereas European bees (other Apis mellifera L. subspecies), common in temperate zones, collect bud exudates of poplar trees (Kumazawa et al, 2002).…”

Section: Discussionmentioning

confidence: 99%

“…The former bee type tends to gather bud exudates of the plant Baccharis dracunculifolia (Asteraceae), whereas European bees (other Apis mellifera L. subspecies), common in temperate zones, collect bud exudates of poplar trees (Kumazawa et al, 2002). Previous studies have revealed differences in antibacterial and antifungal activity of propolis extracts attributable to a difference in chemical composition and concentration of propolis compounds depending on the bee type involved in collection (Fernandes Jr et al, 2001;Silici and Kutluca, 2005;.…”

Section: Discussionmentioning

confidence: 99%

“…Its precise chemical composition is complex and influenced by the phytogeographical origin, the time (i.e. season) of collection, and the type of bees foraging (Cheng and Wong, 1996;Burdock, 1998;Fernandes Jr et al, 2001;Murad et al, 2002;Bankova, 2005a;Silici and Kutluca, 2005). Propolis can be characterized broadly into (i) samples from temperate regions (i.e.…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, in vitro experiments have revealed that propolis could synergize the effect of selected antibiotics (Kedzia and Holderna, 1986;Krol et al, 1993;Scheller et al, 1999;Stepanovic et al, 2003;Fernandes Jr et al, 2005;Scazzocchio et al, 2006). Despite the fact that numerous studies have been published on the antimicrobial activity of propolis from temperate and tropical regions, previous investigations have been limited mainly to samples obtained from either one area, different locations within one country (Kartal et al, 2003;Stepanovic et al, 2003;Uzel et al, 2005;Hayacibara et al, 2005;Popova et al, 2005;Lu et al, 2005;Isla et al, 2005) or on samples collected within the same region by different honeybee races (Fernandes Jr et al, 2001;Silici and Kutluca, 2005;. Comparative biological studies of propolis of different provenance and chemical composition, although important in helping to decide on the best formulation to be used in therapy, are rather limited (Bankova, 2005b).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Comparative study of the antibacterial activity of propolis from different geographical and climatic zones

Seidel

Peyfoon

Watson

et al. 2008

Phytotherapy Research

141

View full text Add to dashboard Cite

Propolis is a natural substance produced by honeybees upon collection and transformation of resins and exudates from plants. Comparative studies on propolis collected from a wide range of countries are crucial for linking its provenance to antibacterial activity and thus ensuring that the beneficial properties of propolis are used more efficiently by the general public. This study reports the in vitro screening of ethanol extracts of propolis (n = 40), collected from a wide range of countries within the tropical, subtropical and temperate zones, and on the comparison of their activity against a range of Gram-positive and Gram-negative bacteria using a broth microdilution assay. The results obtained revealed that propolis extracts were mostly active against Gram-positive bacteria. The samples were subjected to principal component analysis (PCA) in order to model their activity against Gram-positive microorganisms. Three distinct clusters were distinguished in the PCA mapping based on MIC values, categorizing samples with strong (MIC range 3.9-31.25 mg/L), moderate (MIC range 31.25-> or =500 mg/L) and weak antibacterial activity or inactivity (MIC > or = 500 mg/L only). It is hypothesized that for samples of tropical provenance differences in the activity profiles may depend on the climatic characteristics of the collection sites. High antibacterial activity was observed for samples from locations characterized by a wet-tropical rainforest-type climate.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Comparative study of the antibacterial activity of propolis from different geographical and climatic zones

Seidel

Peyfoon

Watson

et al. 2008

Phytotherapy Research

141

View full text Add to dashboard Cite

show abstract

“…Martinez Garcia et al (14) ;Duailibe et al (15) Clinical -Antimicrobial action Azevedo et al (4) ;Santos et al (11) ; Lofuto et al (35) Clinical -Therapeutic action in wound healing Peruchi et al (2) ;Park et al (3) ;Vargas et al (5) ; Fernandes Júnior et al (6) ; Silva et al (7) ;Sforcin et al (8) ; Sforcin et al (9) ;Oliveira et al (10) ; Auricchio et al (35) ; Fernandes Júnior et al (17) ;Machado et al (18) ;Longhini et al (19) ;Sawaya et al (20) ;Fernandes et al (21) ;Fernandes Júnior et al ( 22) ; Muli et al (23) ;Gebara et al (24) ;Fernandes Júnior et al (25) ;Bianchini et al (26) ;Gonçales et al (27) ;Dantas et al (28) ; Ayres et al (29) ;Orsi et al (30) ;Orsi et al (31) ;Sforcin et al (32) ;Sforcin et al (33) ;Orsi et al (34) ; Fernandes Júnior et al (36) ;Fernandes et al (37) ; Araújo et al (38) Experimental -Antimicrobial action Rahal et al (16) Experimental -Therapeutic action in wound healing (1) . Another study, which used propolis ointment on 22 chronic wounds, of which 11 were venous ulcers, seven pressure ulcers, two diabetic ulcers, and two post-trauma injuries, found that necrotic tissue was present in 14 (8.2%) during tissue assessment process.…”

Section: Thematic Focus Approachmentioning

confidence: 99%

Ação terapêutica da própolis em lesões cutâneas

et al. 2009

View full text Add to dashboard Cite

This integrative literature review aimed to analyze the findings of studies that focused on the therapeutic properties of propolis for treatment of skin lesions. Studies were obtained through literature searches using LILACS, MEDLINE, and BDENF databases. The search was limited to publications in Portuguese, English, or Spanish languages from 1980 to 2007. Initially, 1127 publications were identified. However, only 38 publications met the study inclusion criteria. Seven publications (18.42%) were clinical studies and remainder of the 31 publications (81.58%) used "in vitro" or with animal experiments. These publications were focused on the therapeutic properties of propolis in wound healing and on the antimicrobial properties of propolis. Findings suggested the effectiveness of propolis for treating skin lesions, acting as a natural healing and antimicrobial agent whose therapeutic properties depends on the form and place of extraction and concentration of the product. Keywords: Propolis/therapeutic use; Wound healing/nursing RESUMO Trata-se de uma revisão integrativa da literatura que teve como objetivo analisar os estudos que abordam o uso terapêutico da própolis em lesões cutâneas. Os dados foram obtidos por meio de busca nas bases de dados LILACS, MEDLINE, e BDENF, abrangendo o período de 1980 a 2007, nos idiomas português, inglês e espanhol. Identificaram-se 1127 artigos, dos quais 38 atenderam aos critérios de inclusão deste estudo. Destes artigos, 7 (18,4%) eram estudos clínicos e 31 (81,6%) experimentais "in vitro" e em animais. Quanto à abordagem, foram classificados em dois focos temáticos: atuação terapêutica da própolis na cicatrização das lesões e ação antimicrobiana da própolis. A análise dos trabalhos destacou a eficácia da própolis no tratamento de feridas, atuando como agente cicatrizante e antimicrobiano natural, cujas propriedades dependem diretamente da forma e local de extração e concentração do produto. Descritores: Própole/uso terapêutico; Cicatrização de feridas/enfermagem RESUMEN Se trata de una revisión integradora de la literatura con el objetivo de analizar los estudios que abordan el uso terapéutico del própolis en lesiones cutáneas. Los datos fueron obtenidos por medio de la búsqueda en las bases de datos LILACS, MEDLINE, y BDENF, abarcando el período de 1980 al 2007, en los idiomas portugués, inglés y español. Se identificaron 1127 artículos, de los cuales 38 atendieron a los criterios de inclusión del estudio. De estos artículos, 7 (18,4%) eran estudios clínicos y 31 (81,6%) experimentales "in vitro" y en animales. En cuanto al abordaje, fueron clasificados en dos focos temáticos: actuación terapéutica del própolis en la cicatrización de las lesiones y acción antimicrobiana del própolis. El análisis de los trabajos destacó la eficacia del própolis en el tratamiento de heridas, actuando como agente cicatrizante y antimicrobiano natural, cuyas propiedades dependen directamente de la forma y local de extracción y concentración del producto. Descriptores: Própolis/uso terapéut...

show abstract

Pythium insidiosum: inhibitory effects of propolis and geopropolis on hyphal growth

Araújo

Bosco

Sforcin

2016

Brazilian Journal of Microbiology

View full text Add to dashboard Cite

Propolis and geopropolis are resinous products of bees showing antimicrobial effects. There is no data concerning their action against Pythium insidiosum – the causative agent of pythiosis, a pyogranulomatous disease of the subcutaneous tissue that affects mostly horses, dogs and humans. Fragments of 15 isolates of P. insidiodum were incubated with propolis and geopropolis extracts and evaluated for up to seven days to detect the minimal fungicidal concentration (MFC). Propolis inhibited three isolates at 1.0 mg mL−1 after 24 h and all other isolates at 3.4 mg mL−1. Geopropolis led to more variable results, exerting predominantly a fungistatic action than a fungicidal one. Propolis was more efficient than geopropolis in inhibiting P. insidiosum since lower concentrations led to no growth after 24 h. This effect may be due to propolis chemical composition, which has more active compounds than geopropolis. Propolis seemed to be a good candidate for in vivo studies, since treatment with conventional antifungal compounds is difficult in most of the cases, requiring extensive surgical debridement.

show abstract

The antibacterial activity of propolis produced by Apis mellifera L. and Brazilian stingless bees

Cited by 33 publications

References 15 publications

Comparative study of the antibacterial activity of propolis from different geographical and climatic zones

Comparative study of the antibacterial activity of propolis from different geographical and climatic zones

Ação terapêutica da própolis em lesões cutâneas

Pythium insidiosum: inhibitory effects of propolis and geopropolis on hyphal growth

Contact Info

Product

Resources

About