2009
DOI: 10.1590/s0104-66322009000200009
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Study of the microwave vacuum drying process for a granulated product

Abstract: -The objectives of this work were to study and evaluate the process of drying a pharmaceutical granule from 21% to 3 % (d.b.) moisture, also determining the power absorbed by the product, using a microwave assisted vacuum dryer with two absolute pressures: 50 and 75 mbar. A specific objective was to compare the drying kinetics of the microwave assisted vacuum process (MAVP) with two other drying processes, one using hot air convection and the other combining microwaves with hot air convection. The results of s… Show more

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Cited by 17 publications
(9 citation statements)
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“…A more recent work randomly selected, was oriented to investigate dry milling of previously dried grains in a domestic microwave oven [6]. Other work reports the study of a microwave vacuum drying system of granulated material [7], and another one analyzes the temperature variations in barley and canola grains with different moisture contents [8]. This last work details the influence of such grain in temperature uniformity when using microwave-based heating.…”
Section: Introductionmentioning
confidence: 99%
“…A more recent work randomly selected, was oriented to investigate dry milling of previously dried grains in a domestic microwave oven [6]. Other work reports the study of a microwave vacuum drying system of granulated material [7], and another one analyzes the temperature variations in barley and canola grains with different moisture contents [8]. This last work details the influence of such grain in temperature uniformity when using microwave-based heating.…”
Section: Introductionmentioning
confidence: 99%
“…Both mediums of the simulated gastric and intestinal buffer solutions were prepared according to the specications in the International European Pharmacopeia EP, 5th Ed., which are shown in Table 2. 18,19 The gastric uid medium was prepared by dissolving 2 g of sodium chloride in 800 mL of deionized water, and its pH was adjusted to 1.3 using hydrochloric acid. The solution was then diluted with water to obtain 1000 mL of the buffer solution.…”
Section: Methodsmentioning
confidence: 99%
“…The solution was then diluted with water to obtain 1000 mL of the buffer solution. 18,19 Similarly, the intestinal medium was prepared by dissolving about 6.9 g of sodium dihydrogen phosphate and 0.9 g of sodium hydroxide in 800 mL of deionized water. Consequently, the pH of the solution was adjusted to 6.8 using sodium hydroxide.…”
Section: Methodsmentioning
confidence: 99%
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“…Also, increasing vapor pressure in pores of the adsorbent promotes the acceleration of the desorption process [11].…”
Section: Introductionmentioning
confidence: 99%